TY - JOUR
T1 - Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC‐PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen Cladonia metacorallifera
AU - Sepúlveda, Beatriz
AU - Cornejo, Alberto
AU - Bárcenas‐pérez, Daniela
AU - Cheel, José
AU - Areche, Carlos
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
PY - 2022/2
Y1 - 2022/2
N2 - Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification, separation, and tentative characterization of secondary metabolites from natural sources. Twenty‐five compounds were detected from the Antarctic lichen Cladonia metacorallifera for the first time using UHPLC‐PDA/ESI/Orbitrap/MS/MS. Compounds 5 and 7 are reported as new compounds, based on their MS/MS fragmentation routes, and considered as fumarprotocetraric acid derivatives. Besides, ten known phenolic identified as orsellinic acid, ethyl 4‐carboxyorsellinate, psoromic acid isomer, succinprotocetraric acid, siphulellic acid, connorstictic acid, cryptostictic acid, lecanoric acid, lobaric acid and gyrophoric acid are noticed for the first time in the Cladonia genus.
AB - Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification, separation, and tentative characterization of secondary metabolites from natural sources. Twenty‐five compounds were detected from the Antarctic lichen Cladonia metacorallifera for the first time using UHPLC‐PDA/ESI/Orbitrap/MS/MS. Compounds 5 and 7 are reported as new compounds, based on their MS/MS fragmentation routes, and considered as fumarprotocetraric acid derivatives. Besides, ten known phenolic identified as orsellinic acid, ethyl 4‐carboxyorsellinate, psoromic acid isomer, succinprotocetraric acid, siphulellic acid, connorstictic acid, cryptostictic acid, lecanoric acid, lobaric acid and gyrophoric acid are noticed for the first time in the Cladonia genus.
KW - Antarctica
KW - Cladonia
KW - Depsides
KW - Depsidones
KW - ESI/MS/MS
KW - Fumarprotocetraric acid
KW - Lichens
KW - UHPLC
UR - http://www.scopus.com/inward/record.url?scp=85124203948&partnerID=8YFLogxK
U2 - 10.3390/separations9020041
DO - 10.3390/separations9020041
M3 - Article
AN - SCOPUS:85124203948
SN - 2297-8739
VL - 9
JO - Separations
JF - Separations
IS - 2
M1 - 41
ER -