Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan

Resultado de la investigación: Review article

18 Citas (Scopus)

Resumen

Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.

Idioma originalEnglish
Páginas (desde-hasta)1-6
Número de páginas6
PublicaciónBiochemistry and Cell Biology
Volumen87
N.º1
DOI
EstadoPublished - feb 2009

Huella dactilar

Cell Lineage
Epigenomics
Transcription Factors
Genes
Cells
Transcriptome
Mitosis
Cell Division
Transcriptional Activation
Cell Cycle
Gene expression
Machinery
Chemical activation
Association reactions
Tissue
Proteins

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Molecular Biology

Citar esto

Stein, G. S., Zaidi, S. K., Stein, J. L., Lian, J. B., Van Wijnen, A. J., Montecino, M., ... Hassan, M. Q. (2009). Transcription-factor-mediated epigenetic control of cell fate and lineage commitment. Biochemistry and Cell Biology, 87(1), 1-6. https://doi.org/10.1139/O08-094
Stein, Gary S. ; Zaidi, Sayyed K. ; Stein, Janet L. ; Lian, Jane B. ; Van Wijnen, Andre J. ; Montecino, Martin ; Young, Daniel W. ; Javed, Amjad ; Pratap, Jitesh ; Choi, Je Yong ; Ali, Syed A. ; Pande, Sandhya ; Hassan, Mohammad Q. / Transcription-factor-mediated epigenetic control of cell fate and lineage commitment. En: Biochemistry and Cell Biology. 2009 ; Vol. 87, N.º 1. pp. 1-6.
@article{fd6e4b82dea04b639679b2bf3c7903cd,
title = "Transcription-factor-mediated epigenetic control of cell fate and lineage commitment",
abstract = "Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.",
keywords = "Cell cycle, Chromatin, Gene expression, Intranuclear trafficking, Nuclear microenvironment, Runx",
author = "Stein, {Gary S.} and Zaidi, {Sayyed K.} and Stein, {Janet L.} and Lian, {Jane B.} and {Van Wijnen}, {Andre J.} and Martin Montecino and Young, {Daniel W.} and Amjad Javed and Jitesh Pratap and Choi, {Je Yong} and Ali, {Syed A.} and Sandhya Pande and Hassan, {Mohammad Q.}",
year = "2009",
month = "2",
doi = "10.1139/O08-094",
language = "English",
volume = "87",
pages = "1--6",
journal = "Biochemistry and Cell Biology",
issn = "0829-8211",
publisher = "National Research Council of Canada",
number = "1",

}

Stein, GS, Zaidi, SK, Stein, JL, Lian, JB, Van Wijnen, AJ, Montecino, M, Young, DW, Javed, A, Pratap, J, Choi, JY, Ali, SA, Pande, S & Hassan, MQ 2009, 'Transcription-factor-mediated epigenetic control of cell fate and lineage commitment', Biochemistry and Cell Biology, vol. 87, n.º 1, pp. 1-6. https://doi.org/10.1139/O08-094

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment. / Stein, Gary S.; Zaidi, Sayyed K.; Stein, Janet L.; Lian, Jane B.; Van Wijnen, Andre J.; Montecino, Martin; Young, Daniel W.; Javed, Amjad; Pratap, Jitesh; Choi, Je Yong; Ali, Syed A.; Pande, Sandhya; Hassan, Mohammad Q.

En: Biochemistry and Cell Biology, Vol. 87, N.º 1, 02.2009, p. 1-6.

Resultado de la investigación: Review article

TY - JOUR

T1 - Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

AU - Stein, Gary S.

AU - Zaidi, Sayyed K.

AU - Stein, Janet L.

AU - Lian, Jane B.

AU - Van Wijnen, Andre J.

AU - Montecino, Martin

AU - Young, Daniel W.

AU - Javed, Amjad

AU - Pratap, Jitesh

AU - Choi, Je Yong

AU - Ali, Syed A.

AU - Pande, Sandhya

AU - Hassan, Mohammad Q.

PY - 2009/2

Y1 - 2009/2

N2 - Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.

AB - Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.

KW - Cell cycle

KW - Chromatin

KW - Gene expression

KW - Intranuclear trafficking

KW - Nuclear microenvironment

KW - Runx

UR - http://www.scopus.com/inward/record.url?scp=65249129828&partnerID=8YFLogxK

U2 - 10.1139/O08-094

DO - 10.1139/O08-094

M3 - Review article

C2 - 19234518

AN - SCOPUS:65249129828

VL - 87

SP - 1

EP - 6

JO - Biochemistry and Cell Biology

JF - Biochemistry and Cell Biology

SN - 0829-8211

IS - 1

ER -