Towards an intrinsic nucleofugality scale: The leaving group (LG) ability in CH3LG model system

P. Jaramillo, L. R. Domingo, P. Pérez

Resultado de la investigación: Contribución a una revistaArtículo

41 Citas (Scopus)

Resumen

For an important class of organic reactions in which a fragment of the reactants, the leaving group (LG) or nucleofuge (Z), is detached of the substrate bearing the bonding electron pair, the global electrophilicity index of the CH3LG system is proposed as a reliable descriptor of the intrinsic nucleofugality of the LG. The model is illustrated by ranking within a unique relative scale, the LG ability of 28 functional groups commonly involved in substitution and elimination reactions in organic chemistry.

Idioma originalInglés
Páginas (desde-hasta)95-99
Número de páginas5
PublicaciónChemical Physics Letters
Volumen420
N.º1-3
DOI
EstadoPublicada - 10 mar 2006

Áreas temáticas de ASJC Scopus

  • Física y astronomía (todo)
  • Química física y teórica

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