The presence in mice chronically treated with morphine of a substance (S) that modifies morphine responses

F. Huidobro, H. Miranda

Resultado de la investigación: Article

7 Citas (Scopus)

Resumen

A principle that shortens and reduces the intensity of the abstinence syndrome to morphine in white mice was obtained from whole mouse extracts and from urine of mice chronically intoxicated with morphine pellets. Furthermore, a substance that prolongs morphine analgesia was found in extracts from mice implanted with pellets of morphine. At present, it is not known whether both principles are the same. Procedures followed to obtain the indicated principle(s) are described.

Idioma originalEnglish
Páginas (desde-hasta)1099-1105
Número de páginas7
PublicaciónBiochemical Pharmacology
Volumen17
N.º6
EstadoPublished - jun 1968

Huella dactilar

Morphine
Analgesia
Urine
substance S

ASJC Scopus subject areas

  • Pharmacology
  • Biochemistry

Citar esto

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The presence in mice chronically treated with morphine of a substance (S) that modifies morphine responses. / Huidobro, F.; Miranda, H.

En: Biochemical Pharmacology, Vol. 17, N.º 6, 06.1968, p. 1099-1105.

Resultado de la investigación: Article

TY - JOUR

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AB - A principle that shortens and reduces the intensity of the abstinence syndrome to morphine in white mice was obtained from whole mouse extracts and from urine of mice chronically intoxicated with morphine pellets. Furthermore, a substance that prolongs morphine analgesia was found in extracts from mice implanted with pellets of morphine. At present, it is not known whether both principles are the same. Procedures followed to obtain the indicated principle(s) are described.

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