The essential role of chemokines in the selective regulation of lymphocyte homing

María Rosa Bono, Raúl Elgueta, Daniela Sauma, Karina Pino, Fabiola Osorio, Paula Michea, Alberto Fierro, Mario Rosemblatt

Resultado de la investigación: Article

39 Citas (Scopus)

Resumen

Knowledge of lymphocyte migration has become a major issue in our understanding of acquired immunity. The selective migration of naïve, effector, memory and regulatory T-cells is a multiple step process regulated by a specific arrangement of cytokines, chemokines and adhesion receptors that guide these cells to specific locations. Recent research has outlined two major pathways of lymphocyte trafficking under homeostatic and inflammatory conditions, one concerning tropism to cutaneous tissue and a second one related to mucosal-associated sites. In this article we will outline our present understanding of the role of cytokines and chemokines as regulators of lymphocyte migration through tissues.

Idioma originalEnglish
Páginas (desde-hasta)33-43
Número de páginas11
PublicaciónCytokine and Growth Factor Reviews
Volumen18
N.º1-2
DOI
EstadoPublished - 1 feb 2007

Huella dactilar

Lymphocytes
Chemokines
Tissue
Cytokine Receptors
Tropism
T-cells
Chemokine Receptors
Adaptive Immunity
Regulatory T-Lymphocytes
Cytokines
Data storage equipment
Skin
Research

ASJC Scopus subject areas

  • Immunology
  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Biochemistry, Genetics and Molecular Biology(all)

Citar esto

Bono, María Rosa ; Elgueta, Raúl ; Sauma, Daniela ; Pino, Karina ; Osorio, Fabiola ; Michea, Paula ; Fierro, Alberto ; Rosemblatt, Mario. / The essential role of chemokines in the selective regulation of lymphocyte homing. En: Cytokine and Growth Factor Reviews. 2007 ; Vol. 18, N.º 1-2. pp. 33-43.
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The essential role of chemokines in the selective regulation of lymphocyte homing. / Bono, María Rosa; Elgueta, Raúl; Sauma, Daniela; Pino, Karina; Osorio, Fabiola; Michea, Paula; Fierro, Alberto; Rosemblatt, Mario.

En: Cytokine and Growth Factor Reviews, Vol. 18, N.º 1-2, 01.02.2007, p. 33-43.

Resultado de la investigación: Article

TY - JOUR

T1 - The essential role of chemokines in the selective regulation of lymphocyte homing

AU - Bono, María Rosa

AU - Elgueta, Raúl

AU - Sauma, Daniela

AU - Pino, Karina

AU - Osorio, Fabiola

AU - Michea, Paula

AU - Fierro, Alberto

AU - Rosemblatt, Mario

PY - 2007/2/1

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