Resumen
Knowledge of lymphocyte migration has become a major issue in our understanding of acquired immunity. The selective migration of naïve, effector, memory and regulatory T-cells is a multiple step process regulated by a specific arrangement of cytokines, chemokines and adhesion receptors that guide these cells to specific locations. Recent research has outlined two major pathways of lymphocyte trafficking under homeostatic and inflammatory conditions, one concerning tropism to cutaneous tissue and a second one related to mucosal-associated sites. In this article we will outline our present understanding of the role of cytokines and chemokines as regulators of lymphocyte migration through tissues.
Idioma original | English |
---|---|
Páginas (desde-hasta) | 33-43 |
Número de páginas | 11 |
Publicación | Cytokine and Growth Factor Reviews |
Volumen | 18 |
N.º | 1-2 |
DOI | |
Estado | Published - 1 feb 2007 |
Huella dactilar
ASJC Scopus subject areas
- Immunology
- Endocrinology, Diabetes and Metabolism
- Immunology and Allergy
- Biochemistry, Genetics and Molecular Biology(all)
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The essential role of chemokines in the selective regulation of lymphocyte homing. / Bono, María Rosa; Elgueta, Raúl; Sauma, Daniela; Pino, Karina; Osorio, Fabiola; Michea, Paula; Fierro, Alberto; Rosemblatt, Mario.
En: Cytokine and Growth Factor Reviews, Vol. 18, N.º 1-2, 01.02.2007, p. 33-43.Resultado de la investigación: Article
TY - JOUR
T1 - The essential role of chemokines in the selective regulation of lymphocyte homing
AU - Bono, María Rosa
AU - Elgueta, Raúl
AU - Sauma, Daniela
AU - Pino, Karina
AU - Osorio, Fabiola
AU - Michea, Paula
AU - Fierro, Alberto
AU - Rosemblatt, Mario
PY - 2007/2/1
Y1 - 2007/2/1
N2 - Knowledge of lymphocyte migration has become a major issue in our understanding of acquired immunity. The selective migration of naïve, effector, memory and regulatory T-cells is a multiple step process regulated by a specific arrangement of cytokines, chemokines and adhesion receptors that guide these cells to specific locations. Recent research has outlined two major pathways of lymphocyte trafficking under homeostatic and inflammatory conditions, one concerning tropism to cutaneous tissue and a second one related to mucosal-associated sites. In this article we will outline our present understanding of the role of cytokines and chemokines as regulators of lymphocyte migration through tissues.
AB - Knowledge of lymphocyte migration has become a major issue in our understanding of acquired immunity. The selective migration of naïve, effector, memory and regulatory T-cells is a multiple step process regulated by a specific arrangement of cytokines, chemokines and adhesion receptors that guide these cells to specific locations. Recent research has outlined two major pathways of lymphocyte trafficking under homeostatic and inflammatory conditions, one concerning tropism to cutaneous tissue and a second one related to mucosal-associated sites. In this article we will outline our present understanding of the role of cytokines and chemokines as regulators of lymphocyte migration through tissues.
KW - Chemokines
KW - Lymphocyte homing
UR - http://www.scopus.com/inward/record.url?scp=33947179931&partnerID=8YFLogxK
U2 - 10.1016/j.cytogfr.2007.01.004
DO - 10.1016/j.cytogfr.2007.01.004
M3 - Article
C2 - 17324605
AN - SCOPUS:33947179931
VL - 18
SP - 33
EP - 43
JO - Cytokine and Growth Factor Reviews
JF - Cytokine and Growth Factor Reviews
SN - 1359-6101
IS - 1-2
ER -