The CK1 gene family: Expression patterning in zebrafish development

Amelina Albornoz, José M. Yáñez, Claudia Foerster, Celeste Aguirre, Luisa Pereiro, Verónica Burzio, Mauricio Moraga, Ariel E. Reyes, Marcelo Antonelli

Resultado de la investigación: Article

7 Citas (Scopus)

Resumen

Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described in various organisms: CK1α, CK1β, CK1δ, CK1̇and CK1γ. Over the last decade, several members of this family have been involved in development processes related to wnt and sonic hedgehog signalling pathways. However, there is no detailed temporal information on the CK1 family in embryonic stages, even though orthologous genes have been described in several different vertebrate species. In this study, we describe for the first time the cloning and detailed expression pattern of five CK1 zebrafish genes. Sequence analysis revealed that zebrafish CK1 proteins are highly homologous to other vertebrate orthologues. Zebrafish CK1 genes are expressed throughout development in common and different territories. All the genes studied in development show maternal and zygotic expression with the exception of CK1.̇This last gene presents only a zygotic component of expression. In early stages of development CK1 genes are ubiquitously expressed with the exception of CK1.̇In later stages the five CK1 genes are expressed in the brain but not in the same way. This observation probably implicates the CK1 family genes in different and also in redundant functions. This is the first time that a detailed comparison of the expression of CK1 family genes is directly assessed in a vertebrate system throughout development.

Idioma originalEnglish
Páginas (desde-hasta)251-266
Número de páginas16
PublicaciónBiological Research
Volumen40
N.º2
DOI
EstadoPublished - 1 ene 2007

Huella dactilar

Zebrafish
Danio rerio
Genes
Gene Expression
genes
Vertebrates
vertebrates
protein kinases
Zebrafish Proteins
Casein Kinase I
Hedgehogs
Erinaceidae
Cloning
cytosol
Cytosol
Protein Kinases
Sequence Analysis
Organism Cloning
molecular cloning
Brain

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Citar esto

Albornoz, A., Yáñez, J. M., Foerster, C., Aguirre, C., Pereiro, L., Burzio, V., ... Antonelli, M. (2007). The CK1 gene family: Expression patterning in zebrafish development. Biological Research, 40(2), 251-266. https://doi.org/10.4067/S0716-97602007000200015
Albornoz, Amelina ; Yáñez, José M. ; Foerster, Claudia ; Aguirre, Celeste ; Pereiro, Luisa ; Burzio, Verónica ; Moraga, Mauricio ; Reyes, Ariel E. ; Antonelli, Marcelo. / The CK1 gene family : Expression patterning in zebrafish development. En: Biological Research. 2007 ; Vol. 40, N.º 2. pp. 251-266.
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abstract = "Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described in various organisms: CK1α, CK1β, CK1δ, CK1̇and CK1γ. Over the last decade, several members of this family have been involved in development processes related to wnt and sonic hedgehog signalling pathways. However, there is no detailed temporal information on the CK1 family in embryonic stages, even though orthologous genes have been described in several different vertebrate species. In this study, we describe for the first time the cloning and detailed expression pattern of five CK1 zebrafish genes. Sequence analysis revealed that zebrafish CK1 proteins are highly homologous to other vertebrate orthologues. Zebrafish CK1 genes are expressed throughout development in common and different territories. All the genes studied in development show maternal and zygotic expression with the exception of CK1.̇This last gene presents only a zygotic component of expression. In early stages of development CK1 genes are ubiquitously expressed with the exception of CK1.̇In later stages the five CK1 genes are expressed in the brain but not in the same way. This observation probably implicates the CK1 family genes in different and also in redundant functions. This is the first time that a detailed comparison of the expression of CK1 family genes is directly assessed in a vertebrate system throughout development.",
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Albornoz, A, Yáñez, JM, Foerster, C, Aguirre, C, Pereiro, L, Burzio, V, Moraga, M, Reyes, AE & Antonelli, M 2007, 'The CK1 gene family: Expression patterning in zebrafish development', Biological Research, vol. 40, n.º 2, pp. 251-266. https://doi.org/10.4067/S0716-97602007000200015

The CK1 gene family : Expression patterning in zebrafish development. / Albornoz, Amelina; Yáñez, José M.; Foerster, Claudia; Aguirre, Celeste; Pereiro, Luisa; Burzio, Verónica; Moraga, Mauricio; Reyes, Ariel E.; Antonelli, Marcelo.

En: Biological Research, Vol. 40, N.º 2, 01.01.2007, p. 251-266.

Resultado de la investigación: Article

TY - JOUR

T1 - The CK1 gene family

T2 - Expression patterning in zebrafish development

AU - Albornoz, Amelina

AU - Yáñez, José M.

AU - Foerster, Claudia

AU - Aguirre, Celeste

AU - Pereiro, Luisa

AU - Burzio, Verónica

AU - Moraga, Mauricio

AU - Reyes, Ariel E.

AU - Antonelli, Marcelo

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described in various organisms: CK1α, CK1β, CK1δ, CK1̇and CK1γ. Over the last decade, several members of this family have been involved in development processes related to wnt and sonic hedgehog signalling pathways. However, there is no detailed temporal information on the CK1 family in embryonic stages, even though orthologous genes have been described in several different vertebrate species. In this study, we describe for the first time the cloning and detailed expression pattern of five CK1 zebrafish genes. Sequence analysis revealed that zebrafish CK1 proteins are highly homologous to other vertebrate orthologues. Zebrafish CK1 genes are expressed throughout development in common and different territories. All the genes studied in development show maternal and zygotic expression with the exception of CK1.̇This last gene presents only a zygotic component of expression. In early stages of development CK1 genes are ubiquitously expressed with the exception of CK1.̇In later stages the five CK1 genes are expressed in the brain but not in the same way. This observation probably implicates the CK1 family genes in different and also in redundant functions. This is the first time that a detailed comparison of the expression of CK1 family genes is directly assessed in a vertebrate system throughout development.

AB - Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described in various organisms: CK1α, CK1β, CK1δ, CK1̇and CK1γ. Over the last decade, several members of this family have been involved in development processes related to wnt and sonic hedgehog signalling pathways. However, there is no detailed temporal information on the CK1 family in embryonic stages, even though orthologous genes have been described in several different vertebrate species. In this study, we describe for the first time the cloning and detailed expression pattern of five CK1 zebrafish genes. Sequence analysis revealed that zebrafish CK1 proteins are highly homologous to other vertebrate orthologues. Zebrafish CK1 genes are expressed throughout development in common and different territories. All the genes studied in development show maternal and zygotic expression with the exception of CK1.̇This last gene presents only a zygotic component of expression. In early stages of development CK1 genes are ubiquitously expressed with the exception of CK1.̇In later stages the five CK1 genes are expressed in the brain but not in the same way. This observation probably implicates the CK1 family genes in different and also in redundant functions. This is the first time that a detailed comparison of the expression of CK1 family genes is directly assessed in a vertebrate system throughout development.

KW - Casein Kinase 1

KW - CK1

KW - Development

KW - Diencephalon

KW - Expression pattern

KW - Lens

KW - Mesencephalon

KW - Myelencephalon

KW - Otic vesicles

KW - Pectoral fin bud

KW - Retina

KW - Rhombomeres

KW - Tegmentum

KW - Telencephalon

KW - Zebrafish

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U2 - 10.4067/S0716-97602007000200015

DO - 10.4067/S0716-97602007000200015

M3 - Article

C2 - 18064361

AN - SCOPUS:36148945242

VL - 40

SP - 251

EP - 266

JO - Biological Research

JF - Biological Research

SN - 0716-9760

IS - 2

ER -

Albornoz A, Yáñez JM, Foerster C, Aguirre C, Pereiro L, Burzio V y otros. The CK1 gene family: Expression patterning in zebrafish development. Biological Research. 2007 ene 1;40(2):251-266. https://doi.org/10.4067/S0716-97602007000200015