Techniques of structural characterization of dendrimers

Oscar Valdés Lizama, Cristián Vilos, Estebán Duran-Lara

Resultado de la investigación: Contribución a una revistaArtículo de revisión

5 Citas (Scopus)

Resumen

Currently, dendrimers are molecules widely investigated due to their strong potential for biomedical (including diagnostic, drug discovery, and drug delivery platforms) and others applications. The requirements demanded by Food and Drug Administration (FDA) of a new drug application involve several analytical techniques for characterization, which allow understanding the properties of the novel platforms, and to predict their interactions with the biological environment. This work proposes a full description to perform the analytical characterization of dendrimers, including techniques for evaluating the morphology, shape, molecular weight, polydispersity, and purity; as well as methods for the synthesize and conjugation with molecules for targeting.

Idioma originalInglés
Páginas (desde-hasta)2591-2605
Número de páginas15
PublicaciónCurrent Organic Chemistry
Volumen20
N.º24
DOI
EstadoPublicada - 1 oct 2016

Áreas temáticas de ASJC Scopus

  • Química orgánica

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