Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”

Johannes Wittmann, Jochen Klumpp, Andrea I. Moreno Switt, Abdelbaset Yagubi, Hans Wolfgang Ackermann, Martin Wiedmann, Antonet Svircev, John H E Nash, Andrew M. Kropinski

Resultado de la investigación: Article

18 Citas (Scopus)

Resumen

The GenBank database currently contains sequence data for 33 N4-like viruses, with only one, Escherichia phage N4, being formally recognized by the ICTV. The genus N4likevirus is uniquely characterized by that fact that its members possess an extremely large, virion-associated RNA polymerase. Using a variety of proteomic, genomic and phylogenetic tools, we have demonstrated that the N4-like phages are not monophyletic and that N4 is actually a genomic orphan. We propose to create four new genera: “G7cvirus” (consisting of phages G7C, IME11, KBNP21, vB_EcoP_PhAPEC5, vB_EcoP_PhAPEC7, Bp4, EC1-UPM and pSb-1), “Lit1virus” (LIT1, PA26 and vB_PaeP_C2-10_Ab09), “Sp58virus” (SP058 and SP076), and “Dss3virus” (DSS3φ2 and EE36φ1). We propose that coliphage N4, the members of “G7cvirus”, Erwinia phage Ea9-2, and Achromobacter phage JWAlpha should be considered members of the same subfamily, which we tentatively call the “Enquartavirinae”.

Idioma originalEnglish
Páginas (desde-hasta)3053-3062
Número de páginas10
PublicaciónArchives of Virology
Volumen160
N.º12
DOI
EstadoPublished - 23 sep 2015

Huella dactilar

Bacteriophage N4
Genomics
Proteomics
Bacteriophages
Viruses
Achromobacter
Erwinia
Escherichia
Nucleic Acid Databases
DNA-Directed RNA Polymerases
Virion
Databases

ASJC Scopus subject areas

  • Virology
  • Medicine(all)

Citar esto

Wittmann, Johannes ; Klumpp, Jochen ; Moreno Switt, Andrea I. ; Yagubi, Abdelbaset ; Ackermann, Hans Wolfgang ; Wiedmann, Martin ; Svircev, Antonet ; Nash, John H E ; Kropinski, Andrew M. / Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”. En: Archives of Virology. 2015 ; Vol. 160, N.º 12. pp. 3053-3062.
@article{475a5b17ca0a4a3eb477993704174aa9,
title = "Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”",
abstract = "The GenBank database currently contains sequence data for 33 N4-like viruses, with only one, Escherichia phage N4, being formally recognized by the ICTV. The genus N4likevirus is uniquely characterized by that fact that its members possess an extremely large, virion-associated RNA polymerase. Using a variety of proteomic, genomic and phylogenetic tools, we have demonstrated that the N4-like phages are not monophyletic and that N4 is actually a genomic orphan. We propose to create four new genera: “G7cvirus” (consisting of phages G7C, IME11, KBNP21, vB_EcoP_PhAPEC5, vB_EcoP_PhAPEC7, Bp4, EC1-UPM and pSb-1), “Lit1virus” (LIT1, PA26 and vB_PaeP_C2-10_Ab09), “Sp58virus” (SP058 and SP076), and “Dss3virus” (DSS3φ2 and EE36φ1). We propose that coliphage N4, the members of “G7cvirus”, Erwinia phage Ea9-2, and Achromobacter phage JWAlpha should be considered members of the same subfamily, which we tentatively call the “Enquartavirinae”.",
author = "Johannes Wittmann and Jochen Klumpp and {Moreno Switt}, {Andrea I.} and Abdelbaset Yagubi and Ackermann, {Hans Wolfgang} and Martin Wiedmann and Antonet Svircev and Nash, {John H E} and Kropinski, {Andrew M.}",
year = "2015",
month = "9",
day = "23",
doi = "10.1007/s00705-015-2609-6",
language = "English",
volume = "160",
pages = "3053--3062",
journal = "Archives of Virology",
issn = "0304-8608",
publisher = "Springer Wien",
number = "12",

}

Wittmann, J, Klumpp, J, Moreno Switt, AI, Yagubi, A, Ackermann, HW, Wiedmann, M, Svircev, A, Nash, JHE & Kropinski, AM 2015, 'Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”', Archives of Virology, vol. 160, n.º 12, pp. 3053-3062. https://doi.org/10.1007/s00705-015-2609-6

Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”. / Wittmann, Johannes; Klumpp, Jochen; Moreno Switt, Andrea I.; Yagubi, Abdelbaset; Ackermann, Hans Wolfgang; Wiedmann, Martin; Svircev, Antonet; Nash, John H E; Kropinski, Andrew M.

En: Archives of Virology, Vol. 160, N.º 12, 23.09.2015, p. 3053-3062.

Resultado de la investigación: Article

TY - JOUR

T1 - Taxonomic reassessment of N4-like viruses using comparative genomics and proteomics suggests a new subfamily - “Enquartavirinae”

AU - Wittmann, Johannes

AU - Klumpp, Jochen

AU - Moreno Switt, Andrea I.

AU - Yagubi, Abdelbaset

AU - Ackermann, Hans Wolfgang

AU - Wiedmann, Martin

AU - Svircev, Antonet

AU - Nash, John H E

AU - Kropinski, Andrew M.

PY - 2015/9/23

Y1 - 2015/9/23

N2 - The GenBank database currently contains sequence data for 33 N4-like viruses, with only one, Escherichia phage N4, being formally recognized by the ICTV. The genus N4likevirus is uniquely characterized by that fact that its members possess an extremely large, virion-associated RNA polymerase. Using a variety of proteomic, genomic and phylogenetic tools, we have demonstrated that the N4-like phages are not monophyletic and that N4 is actually a genomic orphan. We propose to create four new genera: “G7cvirus” (consisting of phages G7C, IME11, KBNP21, vB_EcoP_PhAPEC5, vB_EcoP_PhAPEC7, Bp4, EC1-UPM and pSb-1), “Lit1virus” (LIT1, PA26 and vB_PaeP_C2-10_Ab09), “Sp58virus” (SP058 and SP076), and “Dss3virus” (DSS3φ2 and EE36φ1). We propose that coliphage N4, the members of “G7cvirus”, Erwinia phage Ea9-2, and Achromobacter phage JWAlpha should be considered members of the same subfamily, which we tentatively call the “Enquartavirinae”.

AB - The GenBank database currently contains sequence data for 33 N4-like viruses, with only one, Escherichia phage N4, being formally recognized by the ICTV. The genus N4likevirus is uniquely characterized by that fact that its members possess an extremely large, virion-associated RNA polymerase. Using a variety of proteomic, genomic and phylogenetic tools, we have demonstrated that the N4-like phages are not monophyletic and that N4 is actually a genomic orphan. We propose to create four new genera: “G7cvirus” (consisting of phages G7C, IME11, KBNP21, vB_EcoP_PhAPEC5, vB_EcoP_PhAPEC7, Bp4, EC1-UPM and pSb-1), “Lit1virus” (LIT1, PA26 and vB_PaeP_C2-10_Ab09), “Sp58virus” (SP058 and SP076), and “Dss3virus” (DSS3φ2 and EE36φ1). We propose that coliphage N4, the members of “G7cvirus”, Erwinia phage Ea9-2, and Achromobacter phage JWAlpha should be considered members of the same subfamily, which we tentatively call the “Enquartavirinae”.

UR - http://www.scopus.com/inward/record.url?scp=84946498489&partnerID=8YFLogxK

U2 - 10.1007/s00705-015-2609-6

DO - 10.1007/s00705-015-2609-6

M3 - Article

C2 - 26395091

AN - SCOPUS:84946498489

VL - 160

SP - 3053

EP - 3062

JO - Archives of Virology

JF - Archives of Virology

SN - 0304-8608

IS - 12

ER -