Synthesis of CdTe QDs/single-walled aluminosilicate nanotubes hybrid compound and their antimicrobial activity on bacteria

Daniela A. Geraldo, Nicolás Arancibia-Miranda, Nicolás A. Villagra, Guido C. Mora, Ramiro Arratia-Perez

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

20 Citas (Scopus)


The use of molecular conjugates of quantum dots (nanocrystalline fluorophores) for biological purposes have received much attention due to their improved biological activity. However, relatively, little is known about the synthesis and application of aluminosilicate nanotubes decorated with quantum dots (QDs) for imaging and treatment of pathogenic bacteria. This paper describes for a first time, the use of single-walled aluminosilicate nanotubes (SWNT) (imogolite) as a one-dimensional template for the in situ growth of mercaptopropionic acid-capped CdTe QDs. This new nanohybrid hydrogel was synthesized by a simple reaction pathway and their enhanced optical properties were monitored by fluorescence and UV-Vis spectroscopy, confirming that the use of these nanotubes favors the confinement effects of net CdTe QDs. In addition, studies of FT-IR spectroscopy and transmission electron microscopy confirmed the non-covalent functionalization of SWNT. Finally, the antimicrobial activity of SWNT coated with CdTe QDs toward three opportunistic multi-resistant pathogens such as Salmonella typhimurium, Acinetobacter baumannii, and Pseudomonas aeruginosa were tested. Growth inhibition tests were conducted by exposing growing bacteria to CdTe QDs/SWNT hybrid compound showing that the new nano-structured composite is a potential antimicrobial agent for heavy metal-resistant bacteria.

Idioma originalInglés
Número de artículo1286
PublicaciónJournal of Nanoparticle Research
EstadoPublicada - 2012

Áreas temáticas de ASJC Scopus

  • Bioingeniería
  • Química General
  • Óptica y física atómica y molecular
  • Modelización y simulación
  • Ciencia de los Materiales General
  • Física de la materia condensada


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