Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions

Carlos A. Escobar, Oscar Donoso-Tauda, Ramiro Araya-Maturana, Dieter Sicker

Resultado de la investigación: Article

9 Citas (Scopus)

Resumen

1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave irradiation conditions on alumina. The latter method proved to be advantageous.

Idioma originalEnglish
Páginas (desde-hasta)166-174
Número de páginas9
PublicaciónSynthetic Communications
Volumen39
N.º1
DOI
EstadoPublished - 1 ene 2009

Huella dactilar

Chalcones
Microwave irradiation
Aluminum Oxide
Benzodiazepines
Methanol
Substitution reactions
2'-hydroxychalcone
1,2-diaminobenzene

ASJC Scopus subject areas

  • Organic Chemistry

Citar esto

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Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions. / Escobar, Carlos A.; Donoso-Tauda, Oscar; Araya-Maturana, Ramiro; Sicker, Dieter.

En: Synthetic Communications, Vol. 39, N.º 1, 01.01.2009, p. 166-174.

Resultado de la investigación: Article

TY - JOUR

T1 - Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions

AU - Escobar, Carlos A.

AU - Donoso-Tauda, Oscar

AU - Araya-Maturana, Ramiro

AU - Sicker, Dieter

PY - 2009/1/1

Y1 - 2009/1/1

N2 - 1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave irradiation conditions on alumina. The latter method proved to be advantageous.

AB - 1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave irradiation conditions on alumina. The latter method proved to be advantageous.

KW - Alumina

KW - Benzodiazepine

KW - Chalcone

KW - Microwave irradiation

KW - Solvent-free synthesis

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U2 - 10.1080/00397910802372517

DO - 10.1080/00397910802372517

M3 - Article

AN - SCOPUS:57449098902

VL - 39

SP - 166

EP - 174

JO - Synthetic Communications

JF - Synthetic Communications

SN - 0039-7911

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