Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives

J. Belmar, J. Alderete, C. Zuniga, C. Jiménez, V. Jiménez, H. Nünez, R. Grandy, A. Yori

Resultado de la investigación: Article

5 Citas (Scopus)

Resumen

3-Methyl- and 3-phenyl-5-pyrazolones were alkylated and formylated. The phenyl derivative was less reactive towards alkylation. However in the formylation step 1-n-alkyl3-methyl- and 1-n-alkyl-3-phenyl-5-pyrazolones showed no difference in reactivity. The alkylated products exist as 5-pyrazolones in chloroform solutions and in dimethylsulfoxide their structure is a 5-hydroxy-pyrazole. Chloroform and dimethyl sulfoxide solutions of 4formyl derivatives have a structure that is better described as 4-hydroxymethylene-5pyrazolone.

Idioma originalEnglish
Páginas (desde-hasta)459-470
Número de páginas12
PublicaciónBoletin de la Sociedad Chilena de Quimica
Volumen46
N.º4
EstadoPublished - 2001

Huella dactilar

Pyrazolones
Chloroform
Dimethyl Sulfoxide
Derivatives
Alkylation

ASJC Scopus subject areas

  • Chemistry(all)

Citar esto

Belmar, J., Alderete, J., Zuniga, C., Jiménez, C., Jiménez, V., Nünez, H., ... Yori, A. (2001). Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives. Boletin de la Sociedad Chilena de Quimica, 46(4), 459-470.
Belmar, J. ; Alderete, J. ; Zuniga, C. ; Jiménez, C. ; Jiménez, V. ; Nünez, H. ; Grandy, R. ; Yori, A. / Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives. En: Boletin de la Sociedad Chilena de Quimica. 2001 ; Vol. 46, N.º 4. pp. 459-470.
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title = "Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives",
abstract = "3-Methyl- and 3-phenyl-5-pyrazolones were alkylated and formylated. The phenyl derivative was less reactive towards alkylation. However in the formylation step 1-n-alkyl3-methyl- and 1-n-alkyl-3-phenyl-5-pyrazolones showed no difference in reactivity. The alkylated products exist as 5-pyrazolones in chloroform solutions and in dimethylsulfoxide their structure is a 5-hydroxy-pyrazole. Chloroform and dimethyl sulfoxide solutions of 4formyl derivatives have a structure that is better described as 4-hydroxymethylene-5pyrazolone.",
keywords = "Alkylpyrazolones, Formylpyrazolones, Pyrazolones, Tautomers",
author = "J. Belmar and J. Alderete and C. Zuniga and C. Jim{\'e}nez and V. Jim{\'e}nez and H. N{\"u}nez and R. Grandy and A. Yori",
year = "2001",
language = "English",
volume = "46",
pages = "459--470",
journal = "Journal of the Chilean Chemical Society",
issn = "0717-9324",
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Belmar, J, Alderete, J, Zuniga, C, Jiménez, C, Jiménez, V, Nünez, H, Grandy, R & Yori, A 2001, 'Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives', Boletin de la Sociedad Chilena de Quimica, vol. 46, n.º 4, pp. 459-470.

Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives. / Belmar, J.; Alderete, J.; Zuniga, C.; Jiménez, C.; Jiménez, V.; Nünez, H.; Grandy, R.; Yori, A.

En: Boletin de la Sociedad Chilena de Quimica, Vol. 46, N.º 4, 2001, p. 459-470.

Resultado de la investigación: Article

TY - JOUR

T1 - Synthesis of 1-n-ALKYL-3-METHYL- And 1-n-ALKYL-3-PHENYL-5-PYRAZOLONES and formyl derivatives

AU - Belmar, J.

AU - Alderete, J.

AU - Zuniga, C.

AU - Jiménez, C.

AU - Jiménez, V.

AU - Nünez, H.

AU - Grandy, R.

AU - Yori, A.

PY - 2001

Y1 - 2001

N2 - 3-Methyl- and 3-phenyl-5-pyrazolones were alkylated and formylated. The phenyl derivative was less reactive towards alkylation. However in the formylation step 1-n-alkyl3-methyl- and 1-n-alkyl-3-phenyl-5-pyrazolones showed no difference in reactivity. The alkylated products exist as 5-pyrazolones in chloroform solutions and in dimethylsulfoxide their structure is a 5-hydroxy-pyrazole. Chloroform and dimethyl sulfoxide solutions of 4formyl derivatives have a structure that is better described as 4-hydroxymethylene-5pyrazolone.

AB - 3-Methyl- and 3-phenyl-5-pyrazolones were alkylated and formylated. The phenyl derivative was less reactive towards alkylation. However in the formylation step 1-n-alkyl3-methyl- and 1-n-alkyl-3-phenyl-5-pyrazolones showed no difference in reactivity. The alkylated products exist as 5-pyrazolones in chloroform solutions and in dimethylsulfoxide their structure is a 5-hydroxy-pyrazole. Chloroform and dimethyl sulfoxide solutions of 4formyl derivatives have a structure that is better described as 4-hydroxymethylene-5pyrazolone.

KW - Alkylpyrazolones

KW - Formylpyrazolones

KW - Pyrazolones

KW - Tautomers

UR - http://www.scopus.com/inward/record.url?scp=23044529649&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:23044529649

VL - 46

SP - 459

EP - 470

JO - Journal of the Chilean Chemical Society

JF - Journal of the Chilean Chemical Society

SN - 0717-9324

IS - 4

ER -