Structure, conformation and biological activity studies on rivularin, a new heliangolide isolated from Leptocarpha rivularis

Rolando Martinez, Victor Kesternich, Hector Carrasco, Carlos Bustos, Silvia Fernandez

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

9 Citas (Scopus)

Resumen

Rivularin, a new heliangolide, was isolated together with leptocarpin as a minor constituent from Leptocarpha rivularis. Structural and conformational studies of this compound were based on elemental analysis. IR spectroscopy, 13C-NMR and 1H-NMR experiments (LIS, NOESY and Py-d5 spectra). Of the four most probable conformations for rivularin, the preferred one is the TC conformation. The 1H-NMR data were compared with those obtained from the synthetic β-epimer 11,13-dihydroleptocarpin, prepared by either catalytic hydrogenation or sodium borohydride reduction of leptocarpin, in order to establish the correct structure and conformation in the heliangolide.

Idioma originalInglés
Páginas (desde-hasta)7-12
Número de páginas6
PublicaciónBoletin de la Sociedad Chilena de Quimica
Volumen43
N.º1
EstadoPublicada - 1998

Áreas temáticas de ASJC Scopus

  • Química (todo)

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