Silver(I) and copper(I) complexes with a Schiff base derived from 2-aminofluorene with promising antibacterial activity

Olga L. Cifuentes-Vaca, Juan Andrades-Lagos, Javier Campanini-Salinas, Antonio Laguna, David Vásquez-Velásquez, M. Concepción Gimeno

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

7 Citas (Scopus)

Resumen

By reaction of 2-aminofluorene with 2-pyridinecarboxaldehyde a new Schiff base (L) is obtained. The reaction of this ligand with Ag(I) and Cu(I) salts in different stoichiometry leads to the complexes [Ag(CF 3 SO 3 )(L)PPh 3 ] (1) or [ML 2 ]A (M = Ag, Cu; A = CF 3 SO 3 , ClO 4 or BF 4 ). Structural characterization by X-ray crystallography has been carried out for complexes [AgL 2 ]ClO 4 (4) and [Ag(L)(PPh 3 ) 2 ](CF 3 SO 3 ) (6), which confirms the chelate nature of L and the presence of Ag⋯H interactions between two molecules. The biological studies show that Schiff base L presents antibacterial activity in Gram-positive bacteria and E. coli. The coordination to silver increases this activity, but the formation of the copper complex does not generate significant changes.

Idioma originalInglés
Páginas (desde-hasta)275-279
Número de páginas5
PublicaciónInorganica Chimica Acta
DOI
EstadoPublicada - 1 abr 2019
Publicado de forma externa

Áreas temáticas de ASJC Scopus

  • Química física y teórica
  • Química inorgánica
  • Química de los materiales

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