Shock séptico en la Unidad de Cuidados Intensivos. Terapéutica avanzada, inmunoparálisis y genómica. Estado del arte

Daniela Arriagada S, Alejandro Donoso F, Pablo Cruces R, Franco Díaz R

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

New and important concepts have emerged for the advanced management of the child with septic shock in the recent decades. Attending physicians in the Pediatric intensive care unit must be fully aware of them to improve patient care in the critical care unit. It should be considered the use of immune therapy only in selected groups of patients. Continuous renal replacement therapies are well tolerated and their early use prevents deleterious fluid overload. Removal of inflammatory mediators by using high volume hemofiltration may play a role in hyperdynamic septic patients. The use of plasmapheresis is recommended in patients with thrombocytopenia-associated multiple organ failure. Extracorporeal support use should be considered in those with refractory septic shock despite goals directed therapy. The immunoparalysis has been associated with nosocomial infections and late mortality. The information from genetic markers may allow early intervention and preventive genomics-based medicine.

Título traducido de la contribuciónSeptic shock in ICU: Advanced therapeutics, immunoparalysis and genomics. State of the art
Idioma originalEspañol
Páginas (desde-hasta)358-365
Número de páginas8
PublicaciónArchivos Argentinos de Pediatria
Volumen12
N.º4
DOI
EstadoPublicada - ago 2014

Palabras clave

  • Extracorporeal support
  • Genomics
  • Immunoparalysis
  • Resuscitation
  • Sepsis
  • Septic shock
  • Treatment

Áreas temáticas de ASJC Scopus

  • Pediatría, perinaltología y salud infantil

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