Scanning electron microscopy and X-ray microanalysis of foreign bodies associated with silastic implants in humans

Arthur H. Tatum, John D. Shelburne, Peter Ingram, Dale N. Robertson, Horacio B. Croxatto, S. Diaz

Resultado de la investigación: Contribución a una revistaArtículo

6 Citas (Scopus)

Resumen

Polydimethylsiloxane (Silastic) capsules containing megestrol acetate have been implanted in subcutaneous tissue as a method of long-term contraception. Histological studies revealed a granulomatous foreign body reaction around these capsules with birefringent crystals in multinucleated giant cells. Although several authors had interpreted these crytals as steroids, this seemed unlikely since the tissue had been processed with organic solvents. Analysis of these crystals by polarization microscopy, scanning electron microscopy, and X-ray microanalysis demonstrated that the material was talc. The talc was probably introduced as a contaminant from gloves during the implantation. Further analysis showed that capsule fragmentation could not have produced the material since Silastic particles could not be detected.

Idioma originalInglés
Páginas (desde-hasta)543-552
Número de páginas10
PublicaciónContraception
Volumen28
N.º6
DOI
EstadoPublicada - 1 ene 1983

Áreas temáticas de ASJC Scopus

  • Medicina reproductiva
  • Ginecología y obstetricia

Huella Profundice en los temas de investigación de 'Scanning electron microscopy and X-ray microanalysis of foreign bodies associated with silastic implants in humans'. En conjunto forman una huella única.

  • Citar esto