Risk factors and pathogenesis of cholesterol gallstones: State of the art

L. Amigo, S. Zanlungo, H. Mendoza, J. F. Miquel, F. Nervi

Resultado de la investigación: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

18 Citas (Scopus)

Resumen

The aim of this article is to present an update of selected aspects of the pathogenesis and risk factors of cholesterol gallstones, a highly prevalent Western disease. The etiology of cholesterol cholelithiasis is considered to be multifactorial, with interaction of genetic and environmental factors. Mechanisms of cholesterol lithogenesis include biliary cholesterol hypersecretion, supersaturation and crystallization, stone formation and growth, and bile stasis within the gallbladder. Each of these various steps could be under genetic control and/or be influenced through intermediate pathogenic steps linked to a variety of environmental factors.

Idioma originalInglés
Páginas (desde-hasta)241-246
Número de páginas6
PublicaciónEuropean Review for Medical and Pharmacological Sciences
Volumen3
N.º6
EstadoPublicada - 1999

Áreas temáticas de ASJC Scopus

  • Farmacología

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