Resumen
The global electrophilicity power, ω, of a series of dipoles and dipolarophiles commonly used in 1,3-dipolar cycloadditions may be conveniently classified within a unique relative scale. The effects of chemical substitution on the electrophilicity of molecules have been evaluated using a representative set of electron-withdrawing and electron-releasing groups for a series of dipoles including nitrone, nitrile oxide and azide derivatives. The absolute scale of electrophilicity is used to rationalize the chemical reactivity of these species as compared to the static reactivity pattern of the reagents involved in the Diels-Alder reactions.
Idioma original | English |
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Páginas (desde-hasta) | 3117-3125 |
Número de páginas | 9 |
Publicación | Tetrahedron |
Volumen | 59 |
N.º | 17 |
DOI | |
Estado | Published - 21 abr 2003 |
Huella dactilar
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Quantitative characterization of the global electrophilicity pattern of some reagents involved in 1,3-dipolar cycloaddition reactions. / Pérez, Patricia; Domingo, Luis R.; Aurell, M. José; Contreras, Renato.
En: Tetrahedron, Vol. 59, N.º 17, 21.04.2003, p. 3117-3125.Resultado de la investigación: Article
TY - JOUR
T1 - Quantitative characterization of the global electrophilicity pattern of some reagents involved in 1,3-dipolar cycloaddition reactions
AU - Pérez, Patricia
AU - Domingo, Luis R.
AU - Aurell, M. José
AU - Contreras, Renato
PY - 2003/4/21
Y1 - 2003/4/21
N2 - The global electrophilicity power, ω, of a series of dipoles and dipolarophiles commonly used in 1,3-dipolar cycloadditions may be conveniently classified within a unique relative scale. The effects of chemical substitution on the electrophilicity of molecules have been evaluated using a representative set of electron-withdrawing and electron-releasing groups for a series of dipoles including nitrone, nitrile oxide and azide derivatives. The absolute scale of electrophilicity is used to rationalize the chemical reactivity of these species as compared to the static reactivity pattern of the reagents involved in the Diels-Alder reactions.
AB - The global electrophilicity power, ω, of a series of dipoles and dipolarophiles commonly used in 1,3-dipolar cycloadditions may be conveniently classified within a unique relative scale. The effects of chemical substitution on the electrophilicity of molecules have been evaluated using a representative set of electron-withdrawing and electron-releasing groups for a series of dipoles including nitrone, nitrile oxide and azide derivatives. The absolute scale of electrophilicity is used to rationalize the chemical reactivity of these species as compared to the static reactivity pattern of the reagents involved in the Diels-Alder reactions.
KW - 1,3-dipolar cycloadditions
KW - Density functional theory
KW - Electrophilicity power
UR - http://www.scopus.com/inward/record.url?scp=0037459857&partnerID=8YFLogxK
U2 - 10.1016/S0040-4020(03)00374-0
DO - 10.1016/S0040-4020(03)00374-0
M3 - Article
AN - SCOPUS:0037459857
VL - 59
SP - 3117
EP - 3125
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 17
ER -