Resumen
Canine brucellosis caused by Brucella canis is a zoonotic disease that causes reproductive alterations in dogs, such as infertility, abortion, and epididymitis. This pathogen is especially prevalent in South America, and due to the lack of official control programs and the growing trend of adopting dogs it constitutes a public health risk that must be addressed. The aim of this study was to determine the prevalence of B. canis infection in kennel, shelter, and household dogs and to characterize the genomic properties of circulating strains, including ure and virB operons and omp25/31 genes. Samples from 771 dogs were obtained, and the infection was detected by blood culture and/or serology in 7.0% of the animals. The complete ure and virB operons and the omp25/31 genes were detected. Interestingly, we found different single-nucleotide polymorphisms (SNPs) in some of the analyzed genes, which could mean a change in the fitness or virulence of these strains. This study provides further evidence about dogs as a source of B. canis strains that can infect people. This also highlights the need to implement official control programs, including the mandatory testing of dogs, especially stray dogs, before adoption.
Idioma original | Inglés |
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Número de artículo | 2073 |
Páginas (desde-hasta) | 1-13 |
Número de páginas | 13 |
Publicación | Animals |
Volumen | 10 |
N.º | 11 |
DOI | |
Estado | Publicada - nov. 2020 |
Publicado de forma externa | Sí |
Áreas temáticas de ASJC Scopus
- Animales y zoología
- Veterinaria General