Physical Activity, Gut Microbiota, and Genetic Background for Children and Adolescents with Autism Spectrum Disorder

Julio Plaza-Diaz, Ana Mei Radar, Aiman Tariq Baig, Marcos Federico Leyba, Maria Macarena Costabel, Juan Pablo Zavala-Crichton, Javier Sanchez-Martinez, Alex E. MacKenzie, Patricio Solis-Urra

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

3 Citas (Scopus)

Resumen

It is estimated that one in 100 children worldwide has been diagnosed with autism spectrum disorder (ASD). Children with ASD frequently suffer from gut dysbiosis and gastrointestinal issues, findings which possibly play a role in the pathogenesis and/or severity of their condition. Physical activity may have a positive effect on the composition of the intestinal microbiota of healthy adults. However, the effect of exercise both on the gastrointestinal problems and intestinal microbiota (and thus possibly on ASD) itself in affected children is unknown. In terms of understanding the physiopathology and manifestations of ASD, analysis of the gut–brain axis holds some promise. Here, we discuss the physiopathology of ASD in terms of genetics and microbiota composition, and how physical activity may be a promising non-pharmaceutical approach to improve ASD-related symptoms.

Idioma originalInglés
Número de artículo1834
PublicaciónChildren
Volumen9
N.º12
DOI
EstadoPublicada - dic. 2022

Áreas temáticas de ASJC Scopus

  • Pediatría, perinaltología y salud infantil

Huella

Profundice en los temas de investigación de 'Physical Activity, Gut Microbiota, and Genetic Background for Children and Adolescents with Autism Spectrum Disorder'. En conjunto forman una huella única.

Citar esto