Pharmacological actions of substance P in the rat vas deferens

H. F. Miranda; W. I. Silva; W. W. Wolstenholme; N. Cuevas; A. Ucros; D. Bustamante; E. H. Fernández

doi:10.1016/0143-4179(91)90149-D

Pharmacological actions of substance P in the rat vas deferens

H. F. Miranda, W. I. Silva, W. W. Wolstenholme, N. Cuevas, A. Ucros, D. Bustamante, E. H. Fernández

Facultad Medicina

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

4 Citas (Scopus)

Resumen

SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth muscle (NK-3 receptor). 2) A neurogenic effect at the pre-synaptic level that results from stimulation of another subtype of SP receptor, located on the nerve terminals (NK-1 receptor).

Idioma original	Inglés
Páginas (desde-hasta)	209-213
Número de páginas	5
Publicación	Neuropeptides
Volumen	18
N.º	4
DOI	https://doi.org/10.1016/0143-4179(91)90149-D
Estado	Publicada - abr. 1991

Áreas temáticas de ASJC Scopus

Endocrinología
Neurología
Sistemas endocrinos y autónomos
Neurociencia celular y molecular

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title = "Pharmacological actions of substance P in the rat vas deferens",

abstract = "SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth muscle (NK-3 receptor). 2) A neurogenic effect at the pre-synaptic level that results from stimulation of another subtype of SP receptor, located on the nerve terminals (NK-1 receptor).",

author = "Miranda, {H. F.} and Silva, {W. I.} and Wolstenholme, {W. W.} and N. Cuevas and A. Ucros and D. Bustamante and Fern{\'a}ndez, {E. H.}",

note = "Funding Information: This work wass upportedb y NIH Grant l-G-12-RR03035OlA awardedt o H. F. Miranda, W. W. Wolstenholmea nd W. I. Silva. The authorsw ish to expresst heir gratitudet o Nydia Rosario for her technicala ssistance.",

year = "1991",

month = apr,

doi = "10.1016/0143-4179(91)90149-D",

language = "English",

volume = "18",

pages = "209--213",

journal = "Neuropeptides",

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publisher = "Churchill Livingstone",

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T1 - Pharmacological actions of substance P in the rat vas deferens

AU - Miranda, H. F.

AU - Silva, W. I.

AU - Wolstenholme, W. W.

AU - Cuevas, N.

AU - Ucros, A.

AU - Bustamante, D.

AU - Fernández, E. H.

N1 - Funding Information: This work wass upportedb y NIH Grant l-G-12-RR03035OlA awardedt o H. F. Miranda, W. W. Wolstenholmea nd W. I. Silva. The authorsw ish to expresst heir gratitudet o Nydia Rosario for her technicala ssistance.

PY - 1991/4

Y1 - 1991/4

N2 - SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth muscle (NK-3 receptor). 2) A neurogenic effect at the pre-synaptic level that results from stimulation of another subtype of SP receptor, located on the nerve terminals (NK-1 receptor).

AB - SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth muscle (NK-3 receptor). 2) A neurogenic effect at the pre-synaptic level that results from stimulation of another subtype of SP receptor, located on the nerve terminals (NK-1 receptor).

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DO - 10.1016/0143-4179(91)90149-D

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AN - SCOPUS:0025857577

SN - 0143-4179

VL - 18

SP - 209

EP - 213

JO - Neuropeptides

JF - Neuropeptides

IS - 4

ER -

Pharmacological actions of substance P in the rat vas deferens

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