Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes

Javier Millán, José Vicente López-Bao, Emilio J. Garcıá, Álvaro Oleaga, Luis Llaneza, Vicente Palacios, Ana De La Torre, Alejandro Rodríguez, Edward J. Dubovi, Fernando Esperón

Resultado de la investigación: Article

16 Citas (Scopus)

Resumen

Wildlife inhabiting human-dominated landscapes is at risk of pathogen spill-over from domestic species. With the aim of gaining knowledge in the dynamics of viral infections in Iberian wolves (Canis lupus) living in anthropized landscapes of northern Spain, we analysed between 2010 and 2013 the samples of 54 wolves by serology and polymerase chain reaction (PCR) for exposure to four pathogenic canine viruses: canine distemper virus (CDV), canine parvovirus-2 (CPV), canine adenovirus 1 and 2 (CAV-1 and CAV-2) and canine herpesvirus. Overall, 76% of the studied wolves presented evidence of exposure to CPV (96% by HI, 66% by PCR) and 75% to CAV (75% by virus neutralization (VN), 76% by PCR, of which 70% CAV-1 and 6% CAV-2). This represents the first detection of CAV-2 infection in a wild carnivore. CPV/CAV-1 co-infection occurred in 51% of the wolves. The probability of wolf exposure to CPV was positively and significantly correlated with farm density in a buffer zone around the place where the wolf was found, indicating that rural dogs might be the origin of CPV infecting wolves. CPV and CAV-1 appear to be enzootic in the Iberian wolf population, which is supported by the absence of seasonal and inter-annual variations in the proportion of positive samples detected. However, while CPV may depend on periodical introductions by dogs, CAV-1 may be maintained within the wolf population. All wolves were negative for exposure to CDV (by VN and PCR) and CHV (by PCR). The absence of acquired immunity against CDV in this population may predispose it to an elevated rate of mortality in the event of a distemper spill-over via dogs.

Idioma originalEnglish
Páginas (desde-hasta)123-134
Número de páginas12
PublicaciónEcoHealth
Volumen13
N.º1
DOI
EstadoPublished - 20 nov 2016

Huella dactilar

Canine Parvovirus
Canidae
virus
polymerase chain reaction
Viruses
Canine Distemper Virus
neutralization
Polymerase Chain Reaction
domestic species
Dogs
buffer zone
immunity
carnivore
annual variation
Canine Adenoviruses
exposure
Distemper
pathogen
Population
farm

ASJC Scopus subject areas

  • Ecology
  • Health, Toxicology and Mutagenesis

Citar esto

Millán, J., López-Bao, J. V., Garcıá, E. J., Oleaga, Á., Llaneza, L., Palacios, V., ... Esperón, F. (2016). Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes. EcoHealth, 13(1), 123-134. https://doi.org/10.1007/s10393-015-1074-8
Millán, Javier ; López-Bao, José Vicente ; Garcıá, Emilio J. ; Oleaga, Álvaro ; Llaneza, Luis ; Palacios, Vicente ; De La Torre, Ana ; Rodríguez, Alejandro ; Dubovi, Edward J. ; Esperón, Fernando. / Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes. En: EcoHealth. 2016 ; Vol. 13, N.º 1. pp. 123-134.
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abstract = "Wildlife inhabiting human-dominated landscapes is at risk of pathogen spill-over from domestic species. With the aim of gaining knowledge in the dynamics of viral infections in Iberian wolves (Canis lupus) living in anthropized landscapes of northern Spain, we analysed between 2010 and 2013 the samples of 54 wolves by serology and polymerase chain reaction (PCR) for exposure to four pathogenic canine viruses: canine distemper virus (CDV), canine parvovirus-2 (CPV), canine adenovirus 1 and 2 (CAV-1 and CAV-2) and canine herpesvirus. Overall, 76{\%} of the studied wolves presented evidence of exposure to CPV (96{\%} by HI, 66{\%} by PCR) and 75{\%} to CAV (75{\%} by virus neutralization (VN), 76{\%} by PCR, of which 70{\%} CAV-1 and 6{\%} CAV-2). This represents the first detection of CAV-2 infection in a wild carnivore. CPV/CAV-1 co-infection occurred in 51{\%} of the wolves. The probability of wolf exposure to CPV was positively and significantly correlated with farm density in a buffer zone around the place where the wolf was found, indicating that rural dogs might be the origin of CPV infecting wolves. CPV and CAV-1 appear to be enzootic in the Iberian wolf population, which is supported by the absence of seasonal and inter-annual variations in the proportion of positive samples detected. However, while CPV may depend on periodical introductions by dogs, CAV-1 may be maintained within the wolf population. All wolves were negative for exposure to CDV (by VN and PCR) and CHV (by PCR). The absence of acquired immunity against CDV in this population may predispose it to an elevated rate of mortality in the event of a distemper spill-over via dogs.",
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Millán, J, López-Bao, JV, Garcıá, EJ, Oleaga, Á, Llaneza, L, Palacios, V, De La Torre, A, Rodríguez, A, Dubovi, EJ & Esperón, F 2016, 'Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes', EcoHealth, vol. 13, n.º 1, pp. 123-134. https://doi.org/10.1007/s10393-015-1074-8

Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes. / Millán, Javier; López-Bao, José Vicente; Garcıá, Emilio J.; Oleaga, Álvaro; Llaneza, Luis; Palacios, Vicente; De La Torre, Ana; Rodríguez, Alejandro; Dubovi, Edward J.; Esperón, Fernando.

En: EcoHealth, Vol. 13, N.º 1, 20.11.2016, p. 123-134.

Resultado de la investigación: Article

TY - JOUR

T1 - Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes

AU - Millán, Javier

AU - López-Bao, José Vicente

AU - Garcıá, Emilio J.

AU - Oleaga, Álvaro

AU - Llaneza, Luis

AU - Palacios, Vicente

AU - De La Torre, Ana

AU - Rodríguez, Alejandro

AU - Dubovi, Edward J.

AU - Esperón, Fernando

PY - 2016/11/20

Y1 - 2016/11/20

N2 - Wildlife inhabiting human-dominated landscapes is at risk of pathogen spill-over from domestic species. With the aim of gaining knowledge in the dynamics of viral infections in Iberian wolves (Canis lupus) living in anthropized landscapes of northern Spain, we analysed between 2010 and 2013 the samples of 54 wolves by serology and polymerase chain reaction (PCR) for exposure to four pathogenic canine viruses: canine distemper virus (CDV), canine parvovirus-2 (CPV), canine adenovirus 1 and 2 (CAV-1 and CAV-2) and canine herpesvirus. Overall, 76% of the studied wolves presented evidence of exposure to CPV (96% by HI, 66% by PCR) and 75% to CAV (75% by virus neutralization (VN), 76% by PCR, of which 70% CAV-1 and 6% CAV-2). This represents the first detection of CAV-2 infection in a wild carnivore. CPV/CAV-1 co-infection occurred in 51% of the wolves. The probability of wolf exposure to CPV was positively and significantly correlated with farm density in a buffer zone around the place where the wolf was found, indicating that rural dogs might be the origin of CPV infecting wolves. CPV and CAV-1 appear to be enzootic in the Iberian wolf population, which is supported by the absence of seasonal and inter-annual variations in the proportion of positive samples detected. However, while CPV may depend on periodical introductions by dogs, CAV-1 may be maintained within the wolf population. All wolves were negative for exposure to CDV (by VN and PCR) and CHV (by PCR). The absence of acquired immunity against CDV in this population may predispose it to an elevated rate of mortality in the event of a distemper spill-over via dogs.

AB - Wildlife inhabiting human-dominated landscapes is at risk of pathogen spill-over from domestic species. With the aim of gaining knowledge in the dynamics of viral infections in Iberian wolves (Canis lupus) living in anthropized landscapes of northern Spain, we analysed between 2010 and 2013 the samples of 54 wolves by serology and polymerase chain reaction (PCR) for exposure to four pathogenic canine viruses: canine distemper virus (CDV), canine parvovirus-2 (CPV), canine adenovirus 1 and 2 (CAV-1 and CAV-2) and canine herpesvirus. Overall, 76% of the studied wolves presented evidence of exposure to CPV (96% by HI, 66% by PCR) and 75% to CAV (75% by virus neutralization (VN), 76% by PCR, of which 70% CAV-1 and 6% CAV-2). This represents the first detection of CAV-2 infection in a wild carnivore. CPV/CAV-1 co-infection occurred in 51% of the wolves. The probability of wolf exposure to CPV was positively and significantly correlated with farm density in a buffer zone around the place where the wolf was found, indicating that rural dogs might be the origin of CPV infecting wolves. CPV and CAV-1 appear to be enzootic in the Iberian wolf population, which is supported by the absence of seasonal and inter-annual variations in the proportion of positive samples detected. However, while CPV may depend on periodical introductions by dogs, CAV-1 may be maintained within the wolf population. All wolves were negative for exposure to CDV (by VN and PCR) and CHV (by PCR). The absence of acquired immunity against CDV in this population may predispose it to an elevated rate of mortality in the event of a distemper spill-over via dogs.

KW - Conservation

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KW - Risk factors

KW - Surveillance

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Millán J, López-Bao JV, Garcıá EJ, Oleaga Á, Llaneza L, Palacios V y otros. Patterns of exposure of iberian wolves (Canis lupus) to canine viruses in human-dominated landscapes. EcoHealth. 2016 nov 20;13(1):123-134. https://doi.org/10.1007/s10393-015-1074-8