Parameterization of the duration of infection stages of serotype O foot-and-mouth disease virus: An analytical review and meta-analysis with application to simulation models

Fernando Mardones, Andrés Perez, Javier Sanchez, Mohammad Alkhamis, Tim Carpenter

Resultado de la investigación: Article

37 Citas (Scopus)

Resumen

Foot-and-mouth disease (FMD) is considered one of the most important infectious diseases of livestock because of the devastating economic consequences that it inflicts in affected regions. The value of critical parameters, such as the duration of the latency or the duration of the infectious periods, which affect the transmission rate of the FMD virus (FMDV), are believed to be influenced by characteristics of the host and the virus. Disease control and surveillance strategies, as well as FMD simulation models, will benefit from improved parameter estimation. The objective of this study was to quantify the distributions of variables associated with the duration of the latency, subclinical, incubation, and infectiousness periods of FMDV transmission. A double independent, systematic review of 19 retrieved publications reporting results from experimental trials, using 295 animals in four reference laboratories, was performed to extract individual values related to FMDV transmission. Probability density functions were fitted to data and a set of regression models were used to identify factors associated with the assessed parameters. Latent, subclinical, incubation, and infectious periods ranged from 3.1 to 4.8, 2 to 2.3, 5.5 to 6.6, and 3.3 to 5.7 days, respectively. Durations were significantly (p < 0.05) associated independently with route of exposure, type of donor, animal species, strains, characteristics of sampling, and clinical signs. These results will contribute to the improvement of disease control and surveillance strategies and stochastic models used to simulate FMD spread and, ultimately, development of cost-effective plans to prevent and control the potential spread of the disease in FMD-free regions of the world.

Idioma originalEnglish
PublicaciónVeterinary Research
Volumen41
N.º4
DOI
EstadoPublished - jul 2010

Huella dactilar

Foot-and-Mouth Disease
Foot-and-Mouth Disease Virus
Foot-and-mouth disease virus
foot-and-mouth disease
meta-analysis
Meta-Analysis
simulation models
serotypes
duration
Viruses
Infection
infection
disease surveillance
virus transmission
disease control
Livestock
Communicable Diseases
Publications
exposure pathways
disease models

ASJC Scopus subject areas

  • veterinary(all)

Citar esto

@article{3fe61a64bbcc406ba565d3b9cae38c4f,
title = "Parameterization of the duration of infection stages of serotype O foot-and-mouth disease virus: An analytical review and meta-analysis with application to simulation models",
abstract = "Foot-and-mouth disease (FMD) is considered one of the most important infectious diseases of livestock because of the devastating economic consequences that it inflicts in affected regions. The value of critical parameters, such as the duration of the latency or the duration of the infectious periods, which affect the transmission rate of the FMD virus (FMDV), are believed to be influenced by characteristics of the host and the virus. Disease control and surveillance strategies, as well as FMD simulation models, will benefit from improved parameter estimation. The objective of this study was to quantify the distributions of variables associated with the duration of the latency, subclinical, incubation, and infectiousness periods of FMDV transmission. A double independent, systematic review of 19 retrieved publications reporting results from experimental trials, using 295 animals in four reference laboratories, was performed to extract individual values related to FMDV transmission. Probability density functions were fitted to data and a set of regression models were used to identify factors associated with the assessed parameters. Latent, subclinical, incubation, and infectious periods ranged from 3.1 to 4.8, 2 to 2.3, 5.5 to 6.6, and 3.3 to 5.7 days, respectively. Durations were significantly (p < 0.05) associated independently with route of exposure, type of donor, animal species, strains, characteristics of sampling, and clinical signs. These results will contribute to the improvement of disease control and surveillance strategies and stochastic models used to simulate FMD spread and, ultimately, development of cost-effective plans to prevent and control the potential spread of the disease in FMD-free regions of the world.",
keywords = "Disease stage, Epidemiologic model, Foot-and-mouth disease, Frailty model, Individual data meta-analysis",
author = "Fernando Mardones and Andr{\'e}s Perez and Javier Sanchez and Mohammad Alkhamis and Tim Carpenter",
year = "2010",
month = "7",
doi = "10.1051/vetres/2010017",
language = "English",
volume = "41",
journal = "Veterinary Research",
issn = "0928-4249",
publisher = "BioMed Central",
number = "4",

}

Parameterization of the duration of infection stages of serotype O foot-and-mouth disease virus : An analytical review and meta-analysis with application to simulation models. / Mardones, Fernando; Perez, Andrés; Sanchez, Javier; Alkhamis, Mohammad; Carpenter, Tim.

En: Veterinary Research, Vol. 41, N.º 4, 07.2010.

Resultado de la investigación: Article

TY - JOUR

T1 - Parameterization of the duration of infection stages of serotype O foot-and-mouth disease virus

T2 - An analytical review and meta-analysis with application to simulation models

AU - Mardones, Fernando

AU - Perez, Andrés

AU - Sanchez, Javier

AU - Alkhamis, Mohammad

AU - Carpenter, Tim

PY - 2010/7

Y1 - 2010/7

N2 - Foot-and-mouth disease (FMD) is considered one of the most important infectious diseases of livestock because of the devastating economic consequences that it inflicts in affected regions. The value of critical parameters, such as the duration of the latency or the duration of the infectious periods, which affect the transmission rate of the FMD virus (FMDV), are believed to be influenced by characteristics of the host and the virus. Disease control and surveillance strategies, as well as FMD simulation models, will benefit from improved parameter estimation. The objective of this study was to quantify the distributions of variables associated with the duration of the latency, subclinical, incubation, and infectiousness periods of FMDV transmission. A double independent, systematic review of 19 retrieved publications reporting results from experimental trials, using 295 animals in four reference laboratories, was performed to extract individual values related to FMDV transmission. Probability density functions were fitted to data and a set of regression models were used to identify factors associated with the assessed parameters. Latent, subclinical, incubation, and infectious periods ranged from 3.1 to 4.8, 2 to 2.3, 5.5 to 6.6, and 3.3 to 5.7 days, respectively. Durations were significantly (p < 0.05) associated independently with route of exposure, type of donor, animal species, strains, characteristics of sampling, and clinical signs. These results will contribute to the improvement of disease control and surveillance strategies and stochastic models used to simulate FMD spread and, ultimately, development of cost-effective plans to prevent and control the potential spread of the disease in FMD-free regions of the world.

AB - Foot-and-mouth disease (FMD) is considered one of the most important infectious diseases of livestock because of the devastating economic consequences that it inflicts in affected regions. The value of critical parameters, such as the duration of the latency or the duration of the infectious periods, which affect the transmission rate of the FMD virus (FMDV), are believed to be influenced by characteristics of the host and the virus. Disease control and surveillance strategies, as well as FMD simulation models, will benefit from improved parameter estimation. The objective of this study was to quantify the distributions of variables associated with the duration of the latency, subclinical, incubation, and infectiousness periods of FMDV transmission. A double independent, systematic review of 19 retrieved publications reporting results from experimental trials, using 295 animals in four reference laboratories, was performed to extract individual values related to FMDV transmission. Probability density functions were fitted to data and a set of regression models were used to identify factors associated with the assessed parameters. Latent, subclinical, incubation, and infectious periods ranged from 3.1 to 4.8, 2 to 2.3, 5.5 to 6.6, and 3.3 to 5.7 days, respectively. Durations were significantly (p < 0.05) associated independently with route of exposure, type of donor, animal species, strains, characteristics of sampling, and clinical signs. These results will contribute to the improvement of disease control and surveillance strategies and stochastic models used to simulate FMD spread and, ultimately, development of cost-effective plans to prevent and control the potential spread of the disease in FMD-free regions of the world.

KW - Disease stage

KW - Epidemiologic model

KW - Foot-and-mouth disease

KW - Frailty model

KW - Individual data meta-analysis

UR - http://www.scopus.com/inward/record.url?scp=77953865927&partnerID=8YFLogxK

U2 - 10.1051/vetres/2010017

DO - 10.1051/vetres/2010017

M3 - Article

C2 - 20205988

AN - SCOPUS:77953865927

VL - 41

JO - Veterinary Research

JF - Veterinary Research

SN - 0928-4249

IS - 4

ER -