Ovum transport in pregnant, pseudopregnant, and cyclic rats and its relationship to estradiol and progesterone blood levels

M. L. Forcelledo, R. Vera, H. B. Croxatto

Resultado de la investigación: Article

25 Citas (Scopus)

Resumen

The time of passage of ova from the oviduct to the uterus and the systemic plasma levels of estradiol and progesterone were investigated in pregnant and pseudopregnant rats, and in rats with regular 4-day cycles. The relationship between ovum transport rates and steroid levels in plasma in these three physiologic conditions were examined. The day following proestrus was designated Day 1 in the three groups. The number and distribution of ova were similar in the three physiologic conditions during the first 3 days, but significant differences appeared thereafter. The major shift in the distribution of ova betwen oviduct and uterus took place between Days 3 and 4 in cycling rats and between Days 4 and 5 in pregnant and pseudopregnant rats. The total number of ova recovered decreased significantly on Day 4 in cycling rats, on Day 5 in pseudopregnant rats, and remained unchanged in pregnant animals. Differences in plasma estradiol levels did not reach statistical significance. Progesterone concentration in plasma was significantly higher in pseudopregnant than in pregnant rats on Days 2 through 5, and it was significantly lower in cycling rats in comparison with the other groups on Days 3 and 4. The estradiol/progesterone ratio differed between groups since Day 1. The results of this study provide definite evidence that the time of passage of ova from the oviduct to the uterus is subject to physiologic regulation in the rat and support the concept that postovulatory changes in sex steroid levels in plasma may contribute to this regulation.

Idioma originalEnglish
Páginas (desde-hasta)760-765
Número de páginas6
PublicaciónBiology of Reproduction
Volumen24
N.º4
EstadoPublished - 1981

Huella dactilar

Ovum Transport
Progesterone
Estradiol
Ovum
Oviducts
Uterus
Steroids
Proestrus

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Embryology
  • Medicine(all)

Citar esto

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title = "Ovum transport in pregnant, pseudopregnant, and cyclic rats and its relationship to estradiol and progesterone blood levels",
abstract = "The time of passage of ova from the oviduct to the uterus and the systemic plasma levels of estradiol and progesterone were investigated in pregnant and pseudopregnant rats, and in rats with regular 4-day cycles. The relationship between ovum transport rates and steroid levels in plasma in these three physiologic conditions were examined. The day following proestrus was designated Day 1 in the three groups. The number and distribution of ova were similar in the three physiologic conditions during the first 3 days, but significant differences appeared thereafter. The major shift in the distribution of ova betwen oviduct and uterus took place between Days 3 and 4 in cycling rats and between Days 4 and 5 in pregnant and pseudopregnant rats. The total number of ova recovered decreased significantly on Day 4 in cycling rats, on Day 5 in pseudopregnant rats, and remained unchanged in pregnant animals. Differences in plasma estradiol levels did not reach statistical significance. Progesterone concentration in plasma was significantly higher in pseudopregnant than in pregnant rats on Days 2 through 5, and it was significantly lower in cycling rats in comparison with the other groups on Days 3 and 4. The estradiol/progesterone ratio differed between groups since Day 1. The results of this study provide definite evidence that the time of passage of ova from the oviduct to the uterus is subject to physiologic regulation in the rat and support the concept that postovulatory changes in sex steroid levels in plasma may contribute to this regulation.",
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Ovum transport in pregnant, pseudopregnant, and cyclic rats and its relationship to estradiol and progesterone blood levels. / Forcelledo, M. L.; Vera, R.; Croxatto, H. B.

En: Biology of Reproduction, Vol. 24, N.º 4, 1981, p. 760-765.

Resultado de la investigación: Article

TY - JOUR

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AU - Vera, R.

AU - Croxatto, H. B.

PY - 1981

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N2 - The time of passage of ova from the oviduct to the uterus and the systemic plasma levels of estradiol and progesterone were investigated in pregnant and pseudopregnant rats, and in rats with regular 4-day cycles. The relationship between ovum transport rates and steroid levels in plasma in these three physiologic conditions were examined. The day following proestrus was designated Day 1 in the three groups. The number and distribution of ova were similar in the three physiologic conditions during the first 3 days, but significant differences appeared thereafter. The major shift in the distribution of ova betwen oviduct and uterus took place between Days 3 and 4 in cycling rats and between Days 4 and 5 in pregnant and pseudopregnant rats. The total number of ova recovered decreased significantly on Day 4 in cycling rats, on Day 5 in pseudopregnant rats, and remained unchanged in pregnant animals. Differences in plasma estradiol levels did not reach statistical significance. Progesterone concentration in plasma was significantly higher in pseudopregnant than in pregnant rats on Days 2 through 5, and it was significantly lower in cycling rats in comparison with the other groups on Days 3 and 4. The estradiol/progesterone ratio differed between groups since Day 1. The results of this study provide definite evidence that the time of passage of ova from the oviduct to the uterus is subject to physiologic regulation in the rat and support the concept that postovulatory changes in sex steroid levels in plasma may contribute to this regulation.

AB - The time of passage of ova from the oviduct to the uterus and the systemic plasma levels of estradiol and progesterone were investigated in pregnant and pseudopregnant rats, and in rats with regular 4-day cycles. The relationship between ovum transport rates and steroid levels in plasma in these three physiologic conditions were examined. The day following proestrus was designated Day 1 in the three groups. The number and distribution of ova were similar in the three physiologic conditions during the first 3 days, but significant differences appeared thereafter. The major shift in the distribution of ova betwen oviduct and uterus took place between Days 3 and 4 in cycling rats and between Days 4 and 5 in pregnant and pseudopregnant rats. The total number of ova recovered decreased significantly on Day 4 in cycling rats, on Day 5 in pseudopregnant rats, and remained unchanged in pregnant animals. Differences in plasma estradiol levels did not reach statistical significance. Progesterone concentration in plasma was significantly higher in pseudopregnant than in pregnant rats on Days 2 through 5, and it was significantly lower in cycling rats in comparison with the other groups on Days 3 and 4. The estradiol/progesterone ratio differed between groups since Day 1. The results of this study provide definite evidence that the time of passage of ova from the oviduct to the uterus is subject to physiologic regulation in the rat and support the concept that postovulatory changes in sex steroid levels in plasma may contribute to this regulation.

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