Mulinane and azorellane diterpenoid biomarkers by GC-MS from a representative Apiaceae (Umbelliferae) species of the Andes

Bernd R.T. Simoneit, Daniel R. Oros, Rudolf Jaffé, Alexandra Didyk-Peña, Carlos Areche, Beatriz Sepúlveda, Borys M. Didyk

Resultado de la investigación: Contribución a una revistaArtículo

Resumen

Extracts of bled resin from Azorella compacta, of the Azorelloideae family from the Andes (>4000 m), were analyzed by gas chromatography-mass spectrometry. The mass spectra of the dominant compounds of the resin and its hydrogenation products were documented. The most abundant compounds were oxygenated diterpenoids, namely mulinadien-20-oic (∆ 11,13 and ∆ 11,14 ) acids, azorell-13-en-20-oic acid, 13α,14β-dihydroxymulin-11-en-20-oic acid, and azorellanol, with a group of azorellenes and mulinadienes. The mass spectra of the novel diterpenoid hydrocarbons with the azorellane and mulinane skeletons were also presented. This study documents the molecular diversity of these diterpenoid classes, and could be of great utility for future organic geochemical, environmental, archeological, pharmaceutical, and forensic chemistry studies.

Idioma originalInglés
Número de artículo684
PublicaciónMolecules
Volumen24
N.º4
DOI
EstadoPublicada - 14 feb 2019

Áreas temáticas de ASJC Scopus

  • Química analítica
  • Química (miscelánea)
  • Medicina molecular
  • Ciencias farmacéuticas
  • Descubrimiento de medicamentos
  • Química física y teórica
  • Química orgánica

Huella Profundice en los temas de investigación de 'Mulinane and azorellane diterpenoid biomarkers by GC-MS from a representative Apiaceae (Umbelliferae) species of the Andes'. En conjunto forman una huella única.

  • Citar esto

    Simoneit, B. R. T., Oros, D. R., Jaffé, R., Didyk-Peña, A., Areche, C., Sepúlveda, B., & Didyk, B. M. (2019). Mulinane and azorellane diterpenoid biomarkers by GC-MS from a representative Apiaceae (Umbelliferae) species of the Andes. Molecules, 24(4), [684]. https://doi.org/10.3390/molecules24040684