Microbial transformation of marine halogenated sesquiterpenes

Aurelio San Martin, Juana Rovirosa, Alvaro Carrasco, Silvia Orejarena, Jorge Soto-Delgado, Renato Contreras, M. Cristina Chamy

Resultado de la investigación: Contribución a una revistaArtículo

2 Citas (Scopus)

Resumen

The sesquiterpene pacifenol is one of the main constituents of the red alga Laurencia claviformis. Earlier work on the semisynthetic derivatives of pacifenol afforded a series of halogenated sesquiterpenes. The aim of the present work was to obtain new hydroxylated derivatives of halogenated sesquiterpenes by means of microbial transformation using Aspergillus níger, Gibberella fujikuroi and Mucor plumbeus. The best results were obtained with M. plumbeus. The microbiological transformation by M. plumbeus of pacifenol, and two semisynthetic derivatives, is described. The structures of the new compounds obtained were determined by spectroscopic means.

Idioma originalInglés
Páginas (desde-hasta)1859-1864
Número de páginas6
PublicaciónNatural Product Communications
Volumen5
N.º12
EstadoPublicada - 2010

Áreas temáticas de ASJC Scopus

  • Medicina (todo)
  • Farmacología
  • Botánica
  • Descubrimiento de medicamentos
  • Medicina complementaria y alternativa

Huella Profundice en los temas de investigación de 'Microbial transformation of marine halogenated sesquiterpenes'. En conjunto forman una huella única.

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    San Martin, A., Rovirosa, J., Carrasco, A., Orejarena, S., Soto-Delgado, J., Contreras, R., & Chamy, M. C. (2010). Microbial transformation of marine halogenated sesquiterpenes. Natural Product Communications, 5(12), 1859-1864.