Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43^A90V mutation display a mild reactive state and release polyP toxic to motoneurons

Fabiola Rojas, Rodrigo Aguilar, Sandra Almeida, Elsa Fritz, Daniela Corvalán, Estibaliz Ampuero, Sebastián Abarzúa, Polett Garcés, Armando Amaro, Iván Diaz, Cristian Arredondo, Nicole Cortes, Mario Sanchez, Constanza Mercado, Lorena Varela-Nallar, Fen Biao Gao, Martin Montecino, Brigitte van Zundert

Universidad Andrés Bello
Facultad Medicina

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Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43^A90V mutation display a mild reactive state and release polyP toxic to motoneurons

Huella

Keyphrases

Neuroscience

Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43 A90V mutation display a mild reactive state and release polyP toxic to motoneurons

Huella

Keyphrases

Neuroscience

Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43^A90V mutation display a mild reactive state and release polyP toxic to motoneurons