Salmonella Typhimurium exhibits fluoroquinolone resistance mediated by the accumulation of the antioxidant molecule H2S in a CysK-dependent manner

Keyphrases

• Salmonella Enterica Serovar Typhimurium (S. Typhimurium) 100%
• Antioxidant Molecules 100%
• CysK 100%
• Fluoroquinolone Resistance 100%
• Ofloxacin 50%
• Cysteine 37%
• Fluoroquinolones 37%
• DNA Damage 25%
• Antibiotic Treatment 25%
• Survival Curve 25%
• Quantitative PCR 12%
• Reactive Oxygen Species 12%
• Low Expression 12%
• Site-directed mutagenesis 12%
• Cysteine Metabolism 12%
• Antibiotic Resistance 12%
• Broth Microdilution 12%
• 4-nitrobenzoic Acid 12%
• Low Template DNA 12%
• Ofloxacin Antibiotic 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Antioxidant 100%
• Salmonella Enterica Serovar Typhimurium 100%
• Quinolone Derivative 100%
• Ofloxacin 100%
• Cysteine 60%
• Survival Rate 40%
• Antibiotics 40%
• Reactive Oxygen Metabolite 20%
• Site-Directed Mutagenesis 20%
• Antibiotic Resistance 20%
• Cysteine Metabolism 20%
• 5,5' Dithiobis(2 Nitrobenzoic Acid) 20%

Immunology and Microbiology

• Salmonella Enterica Serovar Typhimurium 100%
• Minimum Inhibitory Concentration 50%
• Survival Rate 50%
• DNA Damage 50%
• Quantitative Reverse Transcription Polymerase Chain Reaction 25%
• Antimicrobial Resistance 25%
• Site-Directed Mutagenesis 25%
• Broth Dilution 25%