Infecciones invasoras por Haemophilus influenzae tipo b después de la incorporación de la vacuna conjugada al programa ampliado de inmunizaciones en Chile

Pablo Cruces R., Alejandro Donoso F., Jorge Camacho A., Marcela Llorente H.

Resultado de la investigación: Article

13 Citas (Scopus)

Resumen

After almost a decade since the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines in Chile (in a 2-4-6 month schedule), Hib invasive infections have dramatically decreased, albeit they remain to occasionally produce disease in pediatric patients. We report our experience with children whom developed Hib invasive disease in children since 2000 to 2004. Medical records of children with Hib were reviewed in order to describe the epidemiology, main clinical and laboratory findings, management and complications. Twenty three patients (17 male), between 1 and 71 months (median 30 months) were identified: pneumonia (7), meningitis (4), pleuropneumonia (2), empyema (2), sepsis (2), cellulitis (2), meningitis and pleuropneumonia (1), purpura fulminans (1), miositis (1) and epiglottitis (1). No deaths were observed and four patients presented severe sequelae at hospital discharge. Twenty patients were considered vaccine failures. Hib remains as a sporadic cause of severe disease in Chile and thus for physicians should still keep it in mind. Case analysis and active surveillance are necessary to monitor the current immunization regimen.

Idioma originalSpanish
Páginas (desde-hasta)50-54
Número de páginas5
PublicaciónRevista Chilena de Infectologia
Volumen23
N.º1
EstadoPublished - mar 2006

Huella dactilar

Haemophilus influenzae type b
Chile
Immunization
Vaccines
Pleuropneumonia
Infection
Meningitis
Purpura Fulminans
Epiglottitis
Conjugate Vaccines
Empyema
Cellulitis
Medical Records
Sepsis
Pneumonia
Appointments and Schedules
Epidemiology
Pediatrics
Physicians

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

Citar esto

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abstract = "After almost a decade since the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines in Chile (in a 2-4-6 month schedule), Hib invasive infections have dramatically decreased, albeit they remain to occasionally produce disease in pediatric patients. We report our experience with children whom developed Hib invasive disease in children since 2000 to 2004. Medical records of children with Hib were reviewed in order to describe the epidemiology, main clinical and laboratory findings, management and complications. Twenty three patients (17 male), between 1 and 71 months (median 30 months) were identified: pneumonia (7), meningitis (4), pleuropneumonia (2), empyema (2), sepsis (2), cellulitis (2), meningitis and pleuropneumonia (1), purpura fulminans (1), miositis (1) and epiglottitis (1). No deaths were observed and four patients presented severe sequelae at hospital discharge. Twenty patients were considered vaccine failures. Hib remains as a sporadic cause of severe disease in Chile and thus for physicians should still keep it in mind. Case analysis and active surveillance are necessary to monitor the current immunization regimen.",
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Infecciones invasoras por Haemophilus influenzae tipo b después de la incorporación de la vacuna conjugada al programa ampliado de inmunizaciones en Chile. / Cruces R., Pablo; Donoso F., Alejandro; Camacho A., Jorge; Llorente H., Marcela.

En: Revista Chilena de Infectologia, Vol. 23, N.º 1, 03.2006, p. 50-54.

Resultado de la investigación: Article

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