Importance of uterine expulsion of embryos in the interceptive mechanism of postcoital oestradiol in rats

M. E. Ortiz, G. Bastias, O. Darrigrande, H. B. Croxatto

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

4 Citas (Scopus)

Resumen

This study compares the interceptive effectiveness of 1 ftg oestradiol given as a single s.c. injection at 0900 or 1700 hours on Day 1, 2, 3, or 4 of pregnancy in rats. Increasing the interval from ovulation to treatment accelerated the oviducal transport of a larger number of embryos, the majority of which were lost from the genital tract. However, after treatment at 1700 hours on Day 3 the majority of accelerated embryos were retained in the uterus. The number of implanted embryos on Day 14 was equal to the number of eggs remaining in the tract 24 h after treatment. As a consequence, the highest interceptive effectiveness was obtained with treatment given at 1700 hours on Day 2 and at 0900 hours on Day 3 of pregnancy. Accelerated oviducal transport and uterine expulsion of embryos begin to dissociate after Day 2 of pregnancy in the rat. This explains why the most effective treatments to accelerate oviducal transport are not always the most effective to reduce the number of implantations. These data emphasize the importance of retentive and expulsive properties of the uterus for fertility and infertility.

Idioma originalInglés
Páginas (desde-hasta)333-337
Número de páginas5
PublicaciónReproduction, Fertility and Development
Volumen3
N.º3
DOI
EstadoPublicada - 1 ene 1991

Áreas temáticas de ASJC Scopus

  • Biotecnología
  • Medicina reproductiva
  • Animales y zoología
  • Biología molecular
  • Genética
  • Endocrinología
  • Biología del desarrollo

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