Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea

Lautaro Taborga, Katy Díaz, Andrés F. Olea, Paula Reyes-Bravo, Mario E. Flores, Hugo Peña-Cortés, Luis Espinoza

Resultado de la investigación: Article

15 Citas (Scopus)

Resumen

Herein, we explore the potential use of two micelle-forming block copolymers, i.e., Pluronic F-127 and poly(ethylene oxide)-b-poly(caprolactone), for application of fungicide agents. The polymer effect on the in vitro fungicide activity of a series of geranyl orcinol derivatives against Botrytis cinerea has been assessed. The results show that, for all test compounds, the incorporation into micelles, formed by Pluronic F-127, produces a great enhancement of the inhibitory effect on the growth of B. cinerea. For some compounds, at the lowest tested concentration (50 ppm), the percentage of inhibition increases significantly (from 0-10 to 80-90%) when the application is made using a polymer solution instead of an ethanol/water mixture. The synthesis and structural determination of a series of eight geranylphenols/diacetates, which were used as fungicide agents, are also discussed. These results suggest that polymer micelles are promising systems for application of crop-protecting agents.

Idioma originalEnglish
Páginas (desde-hasta)6890-6896
Número de páginas7
PublicaciónJournal of Agricultural and Food Chemistry
Volumen63
N.º31
DOI
EstadoPublished - 12 ago 2015
Publicado de forma externa

Huella dactilar

Botrytis
Fungicides
Micelles
micelles
Botrytis cinerea
Poloxamer
polymers
Polymers
fungicides
composite polymers
Polymer solutions
polyethylene glycol
pesticide application
Block copolymers
Crops
Ethanol
chemical derivatives
ethanol
Derivatives
synthesis

ASJC Scopus subject areas

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

Citar esto

Taborga, L., Díaz, K., Olea, A. F., Reyes-Bravo, P., Flores, M. E., Peña-Cortés, H., & Espinoza, L. (2015). Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea. Journal of Agricultural and Food Chemistry, 63(31), 6890-6896. https://doi.org/10.1021/acs.jafc.5b01920
Taborga, Lautaro ; Díaz, Katy ; Olea, Andrés F. ; Reyes-Bravo, Paula ; Flores, Mario E. ; Peña-Cortés, Hugo ; Espinoza, Luis. / Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea. En: Journal of Agricultural and Food Chemistry. 2015 ; Vol. 63, N.º 31. pp. 6890-6896.
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title = "Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea",
abstract = "Herein, we explore the potential use of two micelle-forming block copolymers, i.e., Pluronic F-127 and poly(ethylene oxide)-b-poly(caprolactone), for application of fungicide agents. The polymer effect on the in vitro fungicide activity of a series of geranyl orcinol derivatives against Botrytis cinerea has been assessed. The results show that, for all test compounds, the incorporation into micelles, formed by Pluronic F-127, produces a great enhancement of the inhibitory effect on the growth of B. cinerea. For some compounds, at the lowest tested concentration (50 ppm), the percentage of inhibition increases significantly (from 0-10 to 80-90{\%}) when the application is made using a polymer solution instead of an ethanol/water mixture. The synthesis and structural determination of a series of eight geranylphenols/diacetates, which were used as fungicide agents, are also discussed. These results suggest that polymer micelles are promising systems for application of crop-protecting agents.",
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author = "Lautaro Taborga and Katy D{\'i}az and Olea, {Andr{\'e}s F.} and Paula Reyes-Bravo and Flores, {Mario E.} and Hugo Pe{\~n}a-Cort{\'e}s and Luis Espinoza",
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Taborga, L, Díaz, K, Olea, AF, Reyes-Bravo, P, Flores, ME, Peña-Cortés, H & Espinoza, L 2015, 'Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea', Journal of Agricultural and Food Chemistry, vol. 63, n.º 31, pp. 6890-6896. https://doi.org/10.1021/acs.jafc.5b01920

Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea. / Taborga, Lautaro; Díaz, Katy; Olea, Andrés F.; Reyes-Bravo, Paula; Flores, Mario E.; Peña-Cortés, Hugo; Espinoza, Luis.

En: Journal of Agricultural and Food Chemistry, Vol. 63, N.º 31, 12.08.2015, p. 6890-6896.

Resultado de la investigación: Article

TY - JOUR

T1 - Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea

AU - Taborga, Lautaro

AU - Díaz, Katy

AU - Olea, Andrés F.

AU - Reyes-Bravo, Paula

AU - Flores, Mario E.

AU - Peña-Cortés, Hugo

AU - Espinoza, Luis

PY - 2015/8/12

Y1 - 2015/8/12

N2 - Herein, we explore the potential use of two micelle-forming block copolymers, i.e., Pluronic F-127 and poly(ethylene oxide)-b-poly(caprolactone), for application of fungicide agents. The polymer effect on the in vitro fungicide activity of a series of geranyl orcinol derivatives against Botrytis cinerea has been assessed. The results show that, for all test compounds, the incorporation into micelles, formed by Pluronic F-127, produces a great enhancement of the inhibitory effect on the growth of B. cinerea. For some compounds, at the lowest tested concentration (50 ppm), the percentage of inhibition increases significantly (from 0-10 to 80-90%) when the application is made using a polymer solution instead of an ethanol/water mixture. The synthesis and structural determination of a series of eight geranylphenols/diacetates, which were used as fungicide agents, are also discussed. These results suggest that polymer micelles are promising systems for application of crop-protecting agents.

AB - Herein, we explore the potential use of two micelle-forming block copolymers, i.e., Pluronic F-127 and poly(ethylene oxide)-b-poly(caprolactone), for application of fungicide agents. The polymer effect on the in vitro fungicide activity of a series of geranyl orcinol derivatives against Botrytis cinerea has been assessed. The results show that, for all test compounds, the incorporation into micelles, formed by Pluronic F-127, produces a great enhancement of the inhibitory effect on the growth of B. cinerea. For some compounds, at the lowest tested concentration (50 ppm), the percentage of inhibition increases significantly (from 0-10 to 80-90%) when the application is made using a polymer solution instead of an ethanol/water mixture. The synthesis and structural determination of a series of eight geranylphenols/diacetates, which were used as fungicide agents, are also discussed. These results suggest that polymer micelles are promising systems for application of crop-protecting agents.

KW - antifungal

KW - Botrytis cinerea

KW - linear geranylphenols

KW - polymer micelles

KW - structural determination

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