Effect of oestradiol delivered from a perioviducal device on ovum transport in mice

J. Zenteno, C. Silva, H. Cardenas, H. B. Croxatto

Resultado de la investigación: Contribución a una revistaArtículo

3 Citas (Scopus)

Resumen

Silastic devices impregnated with oestradiol and blank devices were placed around both oviducts and around skeletal muscle bundles in the forelegs to attain local and systematic delivery, respectively. Another group of mice received an oestradiol-impregnated device around one oviduct and a blank device in the contralateral oviduct. Implantation of blank devices around the oviducts and in the forelegs did not alter ovum transport. Devices impregnated with oestradiol placed around both oviducts produced a dose-dependent delay of ovum transport, which was more pronounced than the effect of devices located in the forelegs. Oviducts receiving an oestradiol-loaded device had a larger retention of ova than did the contralateral oviducts receiving a blank device. These results demonstrate a direct action of oestradiol upon the oviduct to delay ovum transport in the mouse.

Idioma originalInglés
Páginas (desde-hasta)545-548
Número de páginas4
PublicaciónJournal of Reproduction and Fertility
Volumen86
N.º2
DOI
EstadoPublicada - 1 ene 1989

Áreas temáticas de ASJC Scopus

  • Fisiología
  • Embriología
  • Biología molecular
  • Ginecología y obstetricia
  • Biología del desarrollo

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