Effect of microalgae on intestinal inflammation triggered by soybean meal and bacterial infection in zebrafish

Karina Bravo-Tello, Nicole Ehrenfeld, Camila J. Solís, Pilar E. Ulloa, Manuel Hedrera, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja, Carmen G. Feijóo

Resultado de la investigación: Article

4 Citas (Scopus)

Resumen

Soybean meal has been used in many commercial diets for farm fish; despite this component inducing intestinal inflammation. On the other hand, microalgae have increasingly been used as dietary supplements in fish feed. Nevertheless, the vast quantity of microalgae species means that many remain under- or unstudied, thus limiting wide scale commercial application. In this work, we evaluated the effects to zebrafish (Danio rerio) of including Tetraselmis sp (Ts); Phaeodactylum tricornutum (Pt); Chlorella sp (Ch); Nannochloropsis oculata (No); or Nannochloropsis gaditana (Ng) as additives in a soybean meal-based diet on intestinal inflammation and survival after Edwardsiella tarda infection. In larvae fed a soybean meal diet supplemented with Ts, Pt, Ch, or Ng, the quantity of neutrophils present in the intestine drastically decreased as compared to larvae fed only the soybean meal diet. Likewise, Ts or Ch supplements in soybean meal or fishmeal increased zebrafish survival by more than 20% after being challenged. In the case of Ts, the observed effect correlated with an increased number of neutrophils present at the infection site. These results suggest that the inclusion of Ts or Ch in fish diets could allow the use of SBM and at the same time improve performance against pathogen.

Idioma originalEnglish
Número de artículoe0187696
PublicaciónPLoS ONE
Volumen12
N.º11
DOI
EstadoPublished - 1 nov 2017

Huella dactilar

Tetraselmis
Microalgae
Zebrafish
Nutrition
bacterial infections
microalgae
Danio rerio
Soybeans
Bacterial Infections
soybean meal
Meals
Nannochloropsis
inflammation
Diet
Inflammation
Fish
Phaeodactylum tricornutum
diet
Larva
neutrophils

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Citar esto

Bravo-Tello, K., Ehrenfeld, N., Solís, C. J., Ulloa, P. E., Hedrera, M., Pizarro-Guajardo, M., ... Feijóo, C. G. (2017). Effect of microalgae on intestinal inflammation triggered by soybean meal and bacterial infection in zebrafish. PLoS ONE, 12(11), [e0187696]. https://doi.org/10.1371/journal.pone.0187696
Bravo-Tello, Karina ; Ehrenfeld, Nicole ; Solís, Camila J. ; Ulloa, Pilar E. ; Hedrera, Manuel ; Pizarro-Guajardo, Marjorie ; Paredes-Sabja, Daniel ; Feijóo, Carmen G. / Effect of microalgae on intestinal inflammation triggered by soybean meal and bacterial infection in zebrafish. En: PLoS ONE. 2017 ; Vol. 12, N.º 11.
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abstract = "Soybean meal has been used in many commercial diets for farm fish; despite this component inducing intestinal inflammation. On the other hand, microalgae have increasingly been used as dietary supplements in fish feed. Nevertheless, the vast quantity of microalgae species means that many remain under- or unstudied, thus limiting wide scale commercial application. In this work, we evaluated the effects to zebrafish (Danio rerio) of including Tetraselmis sp (Ts); Phaeodactylum tricornutum (Pt); Chlorella sp (Ch); Nannochloropsis oculata (No); or Nannochloropsis gaditana (Ng) as additives in a soybean meal-based diet on intestinal inflammation and survival after Edwardsiella tarda infection. In larvae fed a soybean meal diet supplemented with Ts, Pt, Ch, or Ng, the quantity of neutrophils present in the intestine drastically decreased as compared to larvae fed only the soybean meal diet. Likewise, Ts or Ch supplements in soybean meal or fishmeal increased zebrafish survival by more than 20{\%} after being challenged. In the case of Ts, the observed effect correlated with an increased number of neutrophils present at the infection site. These results suggest that the inclusion of Ts or Ch in fish diets could allow the use of SBM and at the same time improve performance against pathogen.",
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Effect of microalgae on intestinal inflammation triggered by soybean meal and bacterial infection in zebrafish. / Bravo-Tello, Karina; Ehrenfeld, Nicole; Solís, Camila J.; Ulloa, Pilar E.; Hedrera, Manuel; Pizarro-Guajardo, Marjorie; Paredes-Sabja, Daniel; Feijóo, Carmen G.

En: PLoS ONE, Vol. 12, N.º 11, e0187696, 01.11.2017.

Resultado de la investigación: Article

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AU - Hedrera, Manuel

AU - Pizarro-Guajardo, Marjorie

AU - Paredes-Sabja, Daniel

AU - Feijóo, Carmen G.

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Bravo-Tello K, Ehrenfeld N, Solís CJ, Ulloa PE, Hedrera M, Pizarro-Guajardo M y otros. Effect of microalgae on intestinal inflammation triggered by soybean meal and bacterial infection in zebrafish. PLoS ONE. 2017 nov 1;12(11). e0187696. https://doi.org/10.1371/journal.pone.0187696