Efecto del β-glucano: De avena sobre el índice glicémico y carga glicémica de un suplemento nutricional edulcorado con sucralosa en adultos sanos: Un ensayo clínico aleatorizado

Lissé Chiquinquirá Angarita Dávila, Diana Rojas Gómez, José López-Miranda, Karla Parra, María Uzcátegui, Daniel Aparicio, Virginia Céspedes, Robys González, Rendy Chaparro, Mabel Garrido, María Cristina Escobar, Paula Carrasco, Samuel Durán, Michelle Angarita, Nadia Reina, Sandra Wilches-Duran, Modesto Graterol-Rivas, José Chacón, Marco Cerda, Julio Contreras-VelasquezValmore Bermúdez

Resultado de la investigación: Article

Resumen

The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN -β) 59, 8 ± 6,2, with no difference of insulin concentration. Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.

Idioma originalSpanish
Páginas (desde-hasta)77-85
Número de páginas9
PublicaciónArchivos Venezolanos de Farmacologia y Terapeutica
Volumen35
N.º4
EstadoPublished - 2016
Publicado de forma externa

Huella dactilar

trichlorosucrose
Glycemic Index
Glucans
Randomized Controlled Trials
Meals
Glucose
Food Industry
Bread
Intestinal Absorption
Insurance Benefits
Hypoglycemic Agents
LDL Cholesterol
Area Under Curve
Fasting
Healthy Volunteers
Carbohydrates
Glycemic Load
Avena
Insulin
Food

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Citar esto

Dávila, Lissé Chiquinquirá Angarita ; Gómez, Diana Rojas ; López-Miranda, José ; Parra, Karla ; Uzcátegui, María ; Aparicio, Daniel ; Céspedes, Virginia ; González, Robys ; Chaparro, Rendy ; Garrido, Mabel ; Escobar, María Cristina ; Carrasco, Paula ; Durán, Samuel ; Angarita, Michelle ; Reina, Nadia ; Wilches-Duran, Sandra ; Graterol-Rivas, Modesto ; Chacón, José ; Cerda, Marco ; Contreras-Velasquez, Julio ; Bermúdez, Valmore. / Efecto del β-glucano : De avena sobre el índice glicémico y carga glicémica de un suplemento nutricional edulcorado con sucralosa en adultos sanos: Un ensayo clínico aleatorizado. En: Archivos Venezolanos de Farmacologia y Terapeutica. 2016 ; Vol. 35, N.º 4. pp. 77-85.
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abstract = "The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN -β) 59, 8 ± 6,2, with no difference of insulin concentration. Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.",
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author = "D{\'a}vila, {Liss{\'e} Chiquinquir{\'a} Angarita} and G{\'o}mez, {Diana Rojas} and Jos{\'e} L{\'o}pez-Miranda and Karla Parra and Mar{\'i}a Uzc{\'a}tegui and Daniel Aparicio and Virginia C{\'e}spedes and Robys Gonz{\'a}lez and Rendy Chaparro and Mabel Garrido and Escobar, {Mar{\'i}a Cristina} and Paula Carrasco and Samuel Dur{\'a}n and Michelle Angarita and Nadia Reina and Sandra Wilches-Duran and Modesto Graterol-Rivas and Jos{\'e} Chac{\'o}n and Marco Cerda and Julio Contreras-Velasquez and Valmore Berm{\'u}dez",
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journal = "Archivos Venezolanos de Farmacologia y Terapeutica",
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Dávila, LCA, Gómez, DR, López-Miranda, J, Parra, K, Uzcátegui, M, Aparicio, D, Céspedes, V, González, R, Chaparro, R, Garrido, M, Escobar, MC, Carrasco, P, Durán, S, Angarita, M, Reina, N, Wilches-Duran, S, Graterol-Rivas, M, Chacón, J, Cerda, M, Contreras-Velasquez, J & Bermúdez, V 2016, 'Efecto del β-glucano: De avena sobre el índice glicémico y carga glicémica de un suplemento nutricional edulcorado con sucralosa en adultos sanos: Un ensayo clínico aleatorizado', Archivos Venezolanos de Farmacologia y Terapeutica, vol. 35, n.º 4, pp. 77-85.

Efecto del β-glucano : De avena sobre el índice glicémico y carga glicémica de un suplemento nutricional edulcorado con sucralosa en adultos sanos: Un ensayo clínico aleatorizado. / Dávila, Lissé Chiquinquirá Angarita; Gómez, Diana Rojas; López-Miranda, José; Parra, Karla; Uzcátegui, María; Aparicio, Daniel; Céspedes, Virginia; González, Robys; Chaparro, Rendy; Garrido, Mabel; Escobar, María Cristina; Carrasco, Paula; Durán, Samuel; Angarita, Michelle; Reina, Nadia; Wilches-Duran, Sandra; Graterol-Rivas, Modesto; Chacón, José; Cerda, Marco; Contreras-Velasquez, Julio; Bermúdez, Valmore.

En: Archivos Venezolanos de Farmacologia y Terapeutica, Vol. 35, N.º 4, 2016, p. 77-85.

Resultado de la investigación: Article

TY - JOUR

T1 - Efecto del β-glucano

T2 - De avena sobre el índice glicémico y carga glicémica de un suplemento nutricional edulcorado con sucralosa en adultos sanos: Un ensayo clínico aleatorizado

AU - Dávila, Lissé Chiquinquirá Angarita

AU - Gómez, Diana Rojas

AU - López-Miranda, José

AU - Parra, Karla

AU - Uzcátegui, María

AU - Aparicio, Daniel

AU - Céspedes, Virginia

AU - González, Robys

AU - Chaparro, Rendy

AU - Garrido, Mabel

AU - Escobar, María Cristina

AU - Carrasco, Paula

AU - Durán, Samuel

AU - Angarita, Michelle

AU - Reina, Nadia

AU - Wilches-Duran, Sandra

AU - Graterol-Rivas, Modesto

AU - Chacón, José

AU - Cerda, Marco

AU - Contreras-Velasquez, Julio

AU - Bermúdez, Valmore

PY - 2016

Y1 - 2016

N2 - The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN -β) 59, 8 ± 6,2, with no difference of insulin concentration. Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.

AB - The hypoglycemic properties of oat β-glucan is of interest for the food industry and clinical area, for potencial health benefits by reducing glycemic response, serum low-density lipoprotein cholesterol, and glycemic index of meals. There are specific nutritional supplements for diabetics sweetened with sucralose whose glycemic index and glycemic load has not been established. Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults was determined in 13 healthy subjects (6 men and 7 women) old that consumed randomly 4 meals of 50 g of carbohydrates each in different days: a nutritional supplement for diabetics (FN), the nutritional supplement with β-glucan incorporated (FN-β) and two reference food, glucose solution (SG) and white bread (PB). Fasting and postprandial glycemia was measured at times 15, 30, 45, 60, 90 and 120 min. The area under the glycemia curve was lower for both formulas (FN) 12697±993, (FN-β) 11584 ±1171 than for reference products (SG) 13900±1245, y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN) 67, 02 ± 5,69 and glycemic load were intermediate and more lower for the supplement with β-glucan incorporated (FN -β) 59, 8 ± 6,2, with no difference of insulin concentration. Suggesting that the addition of oat-derived β-glucan reduces the rate of intestinal absorption of glucose. This effect should be studied in diabetic.

KW - Glycemic index

KW - Glycemic load

KW - Oat β-glucan

KW - Sucralose

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AN - SCOPUS:85019084152

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EP - 85

JO - Archivos Venezolanos de Farmacologia y Terapeutica

JF - Archivos Venezolanos de Farmacologia y Terapeutica

SN - 0798-0264

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