Ectopic pregnancies associated with low dose progestagen-releasing IUDs

S. Dfaz, H. B. Croxatto, M. Pavez, E. Quinteros, D. Carrillo, L. Simonetti, H. D. Croxatto, S. Rosati

Resultado de la investigación: Article

6 Citas (Scopus)

Resumen

Dimethyl-polysiloxane capsules containing pure progestagens were attached to Tatum's T IUDs and tested in 594 fertile women for contraceptive performance. The control group was represented by 71 women who received identical devices containing barium sulphate instead of steroid and 100 women who received a Copper T-200. The progestagens and the doses tested were megestrol acetate (4.8, 19.2, 26 and 32 ug/day); levonorgestrel (2.1, 3.4 and 8.5 ug/day); norethindrone (18 ug/day); R2323 (28.6 and 45 ug/day); and norgestrienone (26 ug/day). Twelve pregnancies were diagnosed during 5201 woman-months of exposure accumulated within the first year of use among users of the steroid-bearing IUDs. Five of these were ectopic gestations. Ten pregnancies, all uterine, were detected during 1701 woman-months of exposure in the control group. Intrauterine delivery of progestagens by means of a carrier IUD is effective in decreasing the pregnancy rate but it might affect postovulatory events in a way which increases the rate of tubal implantation. Because of this property, progestagen-releasing IUDs should be limited to doses that assure maximal effectiveness to avoid increasing the risk of ectopic pregnancy.

Idioma originalEnglish
Páginas (desde-hasta)259-269
Número de páginas11
PublicaciónContraception
Volumen22
N.º3
DOI
EstadoPublished - 1 ene 1980

Huella dactilar

Ectopic Pregnancy
Progestins
Pregnancy
Norgestrienone
Gestrinone
Steroids
Megestrol Acetate
Barium Sulfate
Norethindrone
Levonorgestrel
Control Groups
Pregnancy Rate
Contraceptive Agents
Capsules
Copper
Equipment and Supplies

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

Citar esto

Dfaz, S., Croxatto, H. B., Pavez, M., Quinteros, E., Carrillo, D., Simonetti, L., ... Rosati, S. (1980). Ectopic pregnancies associated with low dose progestagen-releasing IUDs. Contraception, 22(3), 259-269. https://doi.org/10.1016/S0010-7824(80)80005-9
Dfaz, S. ; Croxatto, H. B. ; Pavez, M. ; Quinteros, E. ; Carrillo, D. ; Simonetti, L. ; Croxatto, H. D. ; Rosati, S. / Ectopic pregnancies associated with low dose progestagen-releasing IUDs. En: Contraception. 1980 ; Vol. 22, N.º 3. pp. 259-269.
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Dfaz, S, Croxatto, HB, Pavez, M, Quinteros, E, Carrillo, D, Simonetti, L, Croxatto, HD & Rosati, S 1980, 'Ectopic pregnancies associated with low dose progestagen-releasing IUDs', Contraception, vol. 22, n.º 3, pp. 259-269. https://doi.org/10.1016/S0010-7824(80)80005-9

Ectopic pregnancies associated with low dose progestagen-releasing IUDs. / Dfaz, S.; Croxatto, H. B.; Pavez, M.; Quinteros, E.; Carrillo, D.; Simonetti, L.; Croxatto, H. D.; Rosati, S.

En: Contraception, Vol. 22, N.º 3, 01.01.1980, p. 259-269.

Resultado de la investigación: Article

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