Early difference in the endocrine profile of long and short lactational amenorrhea

S. Díaz, H. Cárdenas, A. Brandeis, P. Miranda, V. Schiappacasse, A. M. Salvatierra, C. Herreros, M. Serón-Ferré, H. B. Croxatto

Resultado de la investigación: Article

37 Citas (Scopus)

Resumen

The endocrine profiles associated with long and short lactational amenorrhea were assessed in a longitudinal study in which morning blood samples were drawn in 48 women from the first postpartum month until the recovery of ovulation and in a cross-sectional study in which the samples were drawn throughout 24 h at the end of the third postpartum month in 10 fully nursing and amenorrheic women. PRL, LH, FSH, estradiol (E2), progesterone, cortisol, and dehydroepiandrosterone sulfate were measured. In both studies we detected a smaller PRL increase in response to suckling (P < 0.001) and higher E2 levels (P < 0.001) in nursing women who ovulated within 6 months postpartum compared to those in women who did not. Such differences were observed early after delivery when all women were fully nursing and amenorrheic. These results suggest some probable sources of variability in the duration of lactational amenorrhea in our population. The greater PRL response to suckling associated with longer amenorrhea may be due to higher sensitivity of the breast-hypothalamus-pituitary system or a stronger suckling stimulus in this group. Differences in plasma E2 levels between longer and shorter periods of amenorrhea may reflect dissimilar endogenous production, intake, or clearence of estrogens.

Idioma originalEnglish
Páginas (desde-hasta)196-201
Número de páginas6
PublicaciónJournal of Clinical Endocrinology and Metabolism
Volumen72
N.º1
DOI
EstadoPublished - 1991

Huella dactilar

Nursing
Amenorrhea
Postpartum Period
Dehydroepiandrosterone Sulfate
Progesterone
Estradiol
Estrogens
Blood
Ovulation
Hypothalamus
Longitudinal Studies
Plasmas
Recovery
Breast
Cross-Sectional Studies
Population

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Citar esto

Díaz, S. ; Cárdenas, H. ; Brandeis, A. ; Miranda, P. ; Schiappacasse, V. ; Salvatierra, A. M. ; Herreros, C. ; Serón-Ferré, M. ; Croxatto, H. B. / Early difference in the endocrine profile of long and short lactational amenorrhea. En: Journal of Clinical Endocrinology and Metabolism. 1991 ; Vol. 72, N.º 1. pp. 196-201.
@article{3992c3b1235b4f679560a672171330c0,
title = "Early difference in the endocrine profile of long and short lactational amenorrhea",
abstract = "The endocrine profiles associated with long and short lactational amenorrhea were assessed in a longitudinal study in which morning blood samples were drawn in 48 women from the first postpartum month until the recovery of ovulation and in a cross-sectional study in which the samples were drawn throughout 24 h at the end of the third postpartum month in 10 fully nursing and amenorrheic women. PRL, LH, FSH, estradiol (E2), progesterone, cortisol, and dehydroepiandrosterone sulfate were measured. In both studies we detected a smaller PRL increase in response to suckling (P < 0.001) and higher E2 levels (P < 0.001) in nursing women who ovulated within 6 months postpartum compared to those in women who did not. Such differences were observed early after delivery when all women were fully nursing and amenorrheic. These results suggest some probable sources of variability in the duration of lactational amenorrhea in our population. The greater PRL response to suckling associated with longer amenorrhea may be due to higher sensitivity of the breast-hypothalamus-pituitary system or a stronger suckling stimulus in this group. Differences in plasma E2 levels between longer and shorter periods of amenorrhea may reflect dissimilar endogenous production, intake, or clearence of estrogens.",
author = "S. D{\'i}az and H. C{\'a}rdenas and A. Brandeis and P. Miranda and V. Schiappacasse and Salvatierra, {A. M.} and C. Herreros and M. Ser{\'o}n-Ferr{\'e} and Croxatto, {H. B.}",
year = "1991",
doi = "10.1210/jcem-72-1-196",
language = "English",
volume = "72",
pages = "196--201",
journal = "Journal of Clinical Endocrinology and Metabolism",
issn = "0021-972X",
publisher = "The Endocrine Society",
number = "1",

}

Díaz, S, Cárdenas, H, Brandeis, A, Miranda, P, Schiappacasse, V, Salvatierra, AM, Herreros, C, Serón-Ferré, M & Croxatto, HB 1991, 'Early difference in the endocrine profile of long and short lactational amenorrhea', Journal of Clinical Endocrinology and Metabolism, vol. 72, n.º 1, pp. 196-201. https://doi.org/10.1210/jcem-72-1-196

Early difference in the endocrine profile of long and short lactational amenorrhea. / Díaz, S.; Cárdenas, H.; Brandeis, A.; Miranda, P.; Schiappacasse, V.; Salvatierra, A. M.; Herreros, C.; Serón-Ferré, M.; Croxatto, H. B.

En: Journal of Clinical Endocrinology and Metabolism, Vol. 72, N.º 1, 1991, p. 196-201.

Resultado de la investigación: Article

TY - JOUR

T1 - Early difference in the endocrine profile of long and short lactational amenorrhea

AU - Díaz, S.

AU - Cárdenas, H.

AU - Brandeis, A.

AU - Miranda, P.

AU - Schiappacasse, V.

AU - Salvatierra, A. M.

AU - Herreros, C.

AU - Serón-Ferré, M.

AU - Croxatto, H. B.

PY - 1991

Y1 - 1991

N2 - The endocrine profiles associated with long and short lactational amenorrhea were assessed in a longitudinal study in which morning blood samples were drawn in 48 women from the first postpartum month until the recovery of ovulation and in a cross-sectional study in which the samples were drawn throughout 24 h at the end of the third postpartum month in 10 fully nursing and amenorrheic women. PRL, LH, FSH, estradiol (E2), progesterone, cortisol, and dehydroepiandrosterone sulfate were measured. In both studies we detected a smaller PRL increase in response to suckling (P < 0.001) and higher E2 levels (P < 0.001) in nursing women who ovulated within 6 months postpartum compared to those in women who did not. Such differences were observed early after delivery when all women were fully nursing and amenorrheic. These results suggest some probable sources of variability in the duration of lactational amenorrhea in our population. The greater PRL response to suckling associated with longer amenorrhea may be due to higher sensitivity of the breast-hypothalamus-pituitary system or a stronger suckling stimulus in this group. Differences in plasma E2 levels between longer and shorter periods of amenorrhea may reflect dissimilar endogenous production, intake, or clearence of estrogens.

AB - The endocrine profiles associated with long and short lactational amenorrhea were assessed in a longitudinal study in which morning blood samples were drawn in 48 women from the first postpartum month until the recovery of ovulation and in a cross-sectional study in which the samples were drawn throughout 24 h at the end of the third postpartum month in 10 fully nursing and amenorrheic women. PRL, LH, FSH, estradiol (E2), progesterone, cortisol, and dehydroepiandrosterone sulfate were measured. In both studies we detected a smaller PRL increase in response to suckling (P < 0.001) and higher E2 levels (P < 0.001) in nursing women who ovulated within 6 months postpartum compared to those in women who did not. Such differences were observed early after delivery when all women were fully nursing and amenorrheic. These results suggest some probable sources of variability in the duration of lactational amenorrhea in our population. The greater PRL response to suckling associated with longer amenorrhea may be due to higher sensitivity of the breast-hypothalamus-pituitary system or a stronger suckling stimulus in this group. Differences in plasma E2 levels between longer and shorter periods of amenorrhea may reflect dissimilar endogenous production, intake, or clearence of estrogens.

UR - http://www.scopus.com/inward/record.url?scp=0026036293&partnerID=8YFLogxK

U2 - 10.1210/jcem-72-1-196

DO - 10.1210/jcem-72-1-196

M3 - Article

C2 - 1824708

AN - SCOPUS:0026036293

VL - 72

SP - 196

EP - 201

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

SN - 0021-972X

IS - 1

ER -