Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area

Aitor Cevidanes, Laura Altet, Andrea D. Chirife, Tatiana Proboste, Javier Millán

Resultado de la investigación: Article

8 Citas (Scopus)

Resumen

People living at the human/wildlife interface are at risk of becoming infected with Bartonella for which micromammals act as reservoir. We aimed to determine the factors related to the prevalence of Bartonella and its haplotype diversity in micromammals and in their fleas in a Mediterranean peri-urban environment. We analyzed 511 micromammals, chiefly 407 wood mice (Apodemus sylvaticus), captured into Barcelona metropolitan area (Spain) in spring and autumn from 2011 to 2013 in two natural and two adjacent residential areas, their fleas (grouped in 218 monospecific pools) and 29 fetuses from six Bartonella-positive female wood mice. Amplification of a fragment of ITS was carried out by real time PCR. Prevalence was 49% (57% in the dominant species, the wood mouse), and 12 haplotypes were detected. In general, prevalence was higher in those hosts more heavily infested by fleas, coincident with higher rates of capture, in autumn than in spring, and in adults than in juveniles. Prevalence did not differ between natural and residential areas except for one prevalent haplotype, which was more frequent in natural areas. Prevalence in flea pools (58%) was only explained by Bartonella occurrence in the pool host. In 56.4% of the flea pools with identified Bartonella haplotypes, we found the same haplotype in the host and in its flea pool. Prevalence in wood mouse fetuses was 69%, with at least one infected fetus in all litters, and two litters with all the fetuses infected. indicating that vertical transmission might be important in Bartonella epidemiology in the wood mouse. There is a hazard of Bartonella infection for people living in residential areas and those visiting peri-urban natural areas in Barcelona.

Idioma originalEnglish
Páginas (desde-hasta)181-188
Número de páginas8
PublicaciónVeterinary Microbiology
Volumen203
DOI
EstadoPublished - 1 may 2017

Huella dactilar

Bartonella Infections
Bartonella
Siphonaptera
urban areas
Apodemus
Haplotypes
haplotypes
Fetus
residential areas
fetus
infection
litters (young animals)
Murinae
autumn
Apodemus sylvaticus
Spain
Real-Time Polymerase Chain Reaction
Epidemiology
epidemiology
wildlife

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)
  • Medicine(all)

Citar esto

Cevidanes, Aitor ; Altet, Laura ; Chirife, Andrea D. ; Proboste, Tatiana ; Millán, Javier. / Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area. En: Veterinary Microbiology. 2017 ; Vol. 203. pp. 181-188.
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title = "Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area",
abstract = "People living at the human/wildlife interface are at risk of becoming infected with Bartonella for which micromammals act as reservoir. We aimed to determine the factors related to the prevalence of Bartonella and its haplotype diversity in micromammals and in their fleas in a Mediterranean peri-urban environment. We analyzed 511 micromammals, chiefly 407 wood mice (Apodemus sylvaticus), captured into Barcelona metropolitan area (Spain) in spring and autumn from 2011 to 2013 in two natural and two adjacent residential areas, their fleas (grouped in 218 monospecific pools) and 29 fetuses from six Bartonella-positive female wood mice. Amplification of a fragment of ITS was carried out by real time PCR. Prevalence was 49{\%} (57{\%} in the dominant species, the wood mouse), and 12 haplotypes were detected. In general, prevalence was higher in those hosts more heavily infested by fleas, coincident with higher rates of capture, in autumn than in spring, and in adults than in juveniles. Prevalence did not differ between natural and residential areas except for one prevalent haplotype, which was more frequent in natural areas. Prevalence in flea pools (58{\%}) was only explained by Bartonella occurrence in the pool host. In 56.4{\%} of the flea pools with identified Bartonella haplotypes, we found the same haplotype in the host and in its flea pool. Prevalence in wood mouse fetuses was 69{\%}, with at least one infected fetus in all litters, and two litters with all the fetuses infected. indicating that vertical transmission might be important in Bartonella epidemiology in the wood mouse. There is a hazard of Bartonella infection for people living in residential areas and those visiting peri-urban natural areas in Barcelona.",
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Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area. / Cevidanes, Aitor; Altet, Laura; Chirife, Andrea D.; Proboste, Tatiana; Millán, Javier.

En: Veterinary Microbiology, Vol. 203, 01.05.2017, p. 181-188.

Resultado de la investigación: Article

TY - JOUR

T1 - Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area

AU - Cevidanes, Aitor

AU - Altet, Laura

AU - Chirife, Andrea D.

AU - Proboste, Tatiana

AU - Millán, Javier

PY - 2017/5/1

Y1 - 2017/5/1

N2 - People living at the human/wildlife interface are at risk of becoming infected with Bartonella for which micromammals act as reservoir. We aimed to determine the factors related to the prevalence of Bartonella and its haplotype diversity in micromammals and in their fleas in a Mediterranean peri-urban environment. We analyzed 511 micromammals, chiefly 407 wood mice (Apodemus sylvaticus), captured into Barcelona metropolitan area (Spain) in spring and autumn from 2011 to 2013 in two natural and two adjacent residential areas, their fleas (grouped in 218 monospecific pools) and 29 fetuses from six Bartonella-positive female wood mice. Amplification of a fragment of ITS was carried out by real time PCR. Prevalence was 49% (57% in the dominant species, the wood mouse), and 12 haplotypes were detected. In general, prevalence was higher in those hosts more heavily infested by fleas, coincident with higher rates of capture, in autumn than in spring, and in adults than in juveniles. Prevalence did not differ between natural and residential areas except for one prevalent haplotype, which was more frequent in natural areas. Prevalence in flea pools (58%) was only explained by Bartonella occurrence in the pool host. In 56.4% of the flea pools with identified Bartonella haplotypes, we found the same haplotype in the host and in its flea pool. Prevalence in wood mouse fetuses was 69%, with at least one infected fetus in all litters, and two litters with all the fetuses infected. indicating that vertical transmission might be important in Bartonella epidemiology in the wood mouse. There is a hazard of Bartonella infection for people living in residential areas and those visiting peri-urban natural areas in Barcelona.

AB - People living at the human/wildlife interface are at risk of becoming infected with Bartonella for which micromammals act as reservoir. We aimed to determine the factors related to the prevalence of Bartonella and its haplotype diversity in micromammals and in their fleas in a Mediterranean peri-urban environment. We analyzed 511 micromammals, chiefly 407 wood mice (Apodemus sylvaticus), captured into Barcelona metropolitan area (Spain) in spring and autumn from 2011 to 2013 in two natural and two adjacent residential areas, their fleas (grouped in 218 monospecific pools) and 29 fetuses from six Bartonella-positive female wood mice. Amplification of a fragment of ITS was carried out by real time PCR. Prevalence was 49% (57% in the dominant species, the wood mouse), and 12 haplotypes were detected. In general, prevalence was higher in those hosts more heavily infested by fleas, coincident with higher rates of capture, in autumn than in spring, and in adults than in juveniles. Prevalence did not differ between natural and residential areas except for one prevalent haplotype, which was more frequent in natural areas. Prevalence in flea pools (58%) was only explained by Bartonella occurrence in the pool host. In 56.4% of the flea pools with identified Bartonella haplotypes, we found the same haplotype in the host and in its flea pool. Prevalence in wood mouse fetuses was 69%, with at least one infected fetus in all litters, and two litters with all the fetuses infected. indicating that vertical transmission might be important in Bartonella epidemiology in the wood mouse. There is a hazard of Bartonella infection for people living in residential areas and those visiting peri-urban natural areas in Barcelona.

KW - Algerian mouse

KW - Muridae

KW - Shrew

KW - Vector-borne

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U2 - 10.1016/j.vetmic.2017.03.023

DO - 10.1016/j.vetmic.2017.03.023

M3 - Article

AN - SCOPUS:85015806796

VL - 203

SP - 181

EP - 188

JO - Veterinary Microbiology

JF - Veterinary Microbiology

SN - 0378-1135

ER -