Contraceptive efficacy and clinical performance of Nestorone implants in postpartum women

María Rebeca Massai, Soledad Díaz, Eliana Quinteros, María Verónica Reyes, Carmen Herreros, Ana Zepeda, Horacio B. Croxatto, Alfred J. Moo-Young

Resultado de la investigación: Contribución a una revistaArtículo

38 Citas (Scopus)

Resumen

The objective of this study was to evaluate the contraceptive efficacy and clinical performance of a Nestorone subdermal implant (NES) in the postpartum period. NES (n = 100) and Copper T intrauterine device (T-Cu; n = 100) acceptors initiated contraception at 8 weeks postpartum and were followed at monthly intervals during the first year and at 3-month intervals thereafter. Pregnancy rates, breastfeeding performance, infant growth, bleeding pattern, and side effects were assessed. Blood and milk NES concentration were measured. No pregnancy occurred in 2195 and 2145 woman-months of NES implant and T-Cu use, respectively. No effect of NES on lactation and infant growth and no serious adverse events were observed. Lactational amenorrhea was significantly longer in NES users (353 ± 20 days) than in T-Cu users (201 ± 11 days). More NES users (55.8%) experienced prolonged bleedings than did T-Cu users (36.2%). Concentrations of NES in breast milk ranged between 54-135 pmol/liter. The Nestorone implant is a highly effective contraceptive, safe for breastfed infants because the steroid is inactive by the oral route.

Idioma originalInglés
Páginas (desde-hasta)369-376
Número de páginas8
PublicaciónContraception
Volumen64
N.º6
DOI
EstadoPublicada - 1 dic 2001

Áreas temáticas de ASJC Scopus

  • Medicina reproductiva
  • Ginecología y obstetricia

Huella Profundice en los temas de investigación de 'Contraceptive efficacy and clinical performance of Nestorone implants in postpartum women'. En conjunto forman una huella única.

  • Citar esto

    Massai, M. R., Díaz, S., Quinteros, E., Reyes, M. V., Herreros, C., Zepeda, A., Croxatto, H. B., & Moo-Young, A. J. (2001). Contraceptive efficacy and clinical performance of Nestorone implants in postpartum women. Contraception, 64(6), 369-376. https://doi.org/10.1016/S0010-7824(01)00259-1