Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular

Christof Fischer Wiethuchter, Valentina Lepe, Álvaro Opazo, Álvaro Luzio, Ignacio Troncoso, Carolina Hernandez

Resultado de la investigación: Article

Resumen

Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).

Idioma originalSpanish
Páginas (desde-hasta)729-733
Número de páginas5
PublicaciónRevista de Investigaciones Veterinarias del Peru
Volumen29
N.º3
DOI
EstadoPublished - 1 ene 2018

Huella dactilar

transforming growth factor beta 1
synovial fluid
osteoarthritis
Synovial Fluid
Osteoarthritis
Transforming Growth Factor beta
Dogs
dogs
transforming growth factors
Transforming Growth Factors
extracellular matrix
cartilage
Cartilage
Extracellular Matrix
Canidae
cytokines
Joints
Enzyme-Linked Immunosorbent Assay
enzyme-linked immunosorbent assay
Pathology

ASJC Scopus subject areas

  • veterinary(all)

Citar esto

Wiethuchter, Christof Fischer ; Lepe, Valentina ; Opazo, Álvaro ; Luzio, Álvaro ; Troncoso, Ignacio ; Hernandez, Carolina. / Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular. En: Revista de Investigaciones Veterinarias del Peru. 2018 ; Vol. 29, N.º 3. pp. 729-733.
@article{20adc8b73eee484e969d57bccc810ed2,
title = "Comparaci{\'o}n de la concentraci{\'o}n del factor de crecimiento transformante Beta 1 (TGF-β1) en l{\'i}quido sinovial de perros con y sin enfermedad degenerativa articular",
abstract = "Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).",
keywords = "Canines, Synovial fluid, Transforming growth factor β1",
author = "Wiethuchter, {Christof Fischer} and Valentina Lepe and {\'A}lvaro Opazo and {\'A}lvaro Luzio and Ignacio Troncoso and Carolina Hernandez",
year = "2018",
month = "1",
day = "1",
doi = "10.15381/rivep.v29i3.14758",
language = "Spanish",
volume = "29",
pages = "729--733",
journal = "Revista de Investigaciones Veterinarias del Peru",
issn = "1682-3419",
publisher = "Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos",
number = "3",

}

Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular. / Wiethuchter, Christof Fischer; Lepe, Valentina; Opazo, Álvaro; Luzio, Álvaro; Troncoso, Ignacio; Hernandez, Carolina.

En: Revista de Investigaciones Veterinarias del Peru, Vol. 29, N.º 3, 01.01.2018, p. 729-733.

Resultado de la investigación: Article

TY - JOUR

T1 - Comparación de la concentración del factor de crecimiento transformante Beta 1 (TGF-β1) en líquido sinovial de perros con y sin enfermedad degenerativa articular

AU - Wiethuchter, Christof Fischer

AU - Lepe, Valentina

AU - Opazo, Álvaro

AU - Luzio, Álvaro

AU - Troncoso, Ignacio

AU - Hernandez, Carolina

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).

AB - Degenerative joint disease (DJD) is a non-inflammatory pathology and characterized to be progressive, structural, and functional. The transforming growth factor Beta 1 (TGF-β1) is a regulatory cytokine participating in the production and deposition of extracellular matrix in various tissues, including joint cartilage. The aim of the present study was to compare the concentrations of transforming growth factor β1 in canine synovial fluid with (n=12) and without DJD (n=11), determined by an ELISA test. The mean concentration of TGB-β1 in dogs without DJD was 16.8 ± 7.1 ng/ml, while in dogs with DJD it was 10.3 ± 3.5 ng/ml (p <0.05).

KW - Canines

KW - Synovial fluid

KW - Transforming growth factor β1

UR - http://www.scopus.com/inward/record.url?scp=85054557421&partnerID=8YFLogxK

U2 - 10.15381/rivep.v29i3.14758

DO - 10.15381/rivep.v29i3.14758

M3 - Article

AN - SCOPUS:85054557421

VL - 29

SP - 729

EP - 733

JO - Revista de Investigaciones Veterinarias del Peru

JF - Revista de Investigaciones Veterinarias del Peru

SN - 1682-3419

IS - 3

ER -