Caracterización y sensibilidad antimicrobiana de Staphylococcus coagulasa-positivos aislados en un hospital clínico veterinario en Chile

Francisco Abusleme, Nicolás Galarce, Mario Quezada-Aguiluz, Daniela Iragüen, Gerardo González-Rocha

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

There is limited information about the prevalence and antimicrobial susceptibility of coagulase-positive Staphylococcus (CoPS) strains in veterinary settings in Chile. The aim of this observational study was to identify and characterize CoPS strains from dogs, owners, veterinary professionals and surfaces in a veterinary teaching hospital at Universidad de Chile to determine the presence of methicillin-resistant strains and evaluate the genetic relationship among the strains. Veterinarians (n = 24), surfaces (n = 10), and healthy dogs (n = 40) and their respective owners (n = 40) were sampled for CoPS. Isolates were identified by PCR and antimicrobial susceptibility was assessed by the disk diffusion method and MIC. The presence of the mecA gene was evaluated by PCR, and the genetic relationship among the strains was established by PFGE. A total of 45 CoPS strains were obtained, eight from veterinary professionals, three from hospital surfaces, eight from owners and 26 from dogs. Nine of the strains were resistant to methicillin (20%), and all of them carried the mecA gene. A high percentage of the strains was resistant to clindamycin (33.3%). Additionally, the isolated CoPS showed high genetic diversity. This study suggests that veterinarians are in high risk of harboring methicillin-resistant CoPS (25% versus 2.5% from owners) and our results provide evidence that clindamycin could not be an empiric alternative for CoPS in the analyzed hospital. This is the first report of methicillin-resistant CoPS in veterinary settings in Chile, considering humans, pets and surfaces.

Título traducido de la contribuciónCharacterization and antimicrobial susceptibility of coagulase-positive Staphylococcus isolated in a veterinary teaching hospital in Chile
Idioma originalEspañol
PublicaciónRevista Argentina de Microbiologia
DOI
EstadoEn prensa - 2022
Publicado de forma externa

Palabras clave

  • Antimicrobial resistance
  • Methicillin-resistant Staphylococcus aureus
  • Methicillin-resistant Staphylococcus pseudintermedius
  • Pets

Áreas temáticas de ASJC Scopus

  • Microbiología
  • Microbiología (médica)

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