Cólico biliar inducido por morfina

Zoltán Berger, Mario Arcos, Fernanda Matamala, Claudia Rojas

Resultado de la investigación: Article

Resumen

Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epi-gastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics. Transaminases elevated from previously normal value to over 1,000 U/L, and returned to the normal level without further treatment after several days. Magnetic resonance cholangiography showed normal fine bile duct, without stones. This transient increase in hepatic enzymes was considered as a consequence of high biliary pressure secondary to morphine-induced spastic contraction of Oddi’s sphincter and a consecutive hepatocellular necrosis.

Idioma originalSpanish
Páginas (desde-hasta)406-409
Número de páginas4
PublicaciónRevista Medica de Chile
Volumen145
N.º3
DOI
EstadoPublished - 2017
Publicado de forma externa

Huella dactilar

Morphine
Abdominal Pain
Sphincter of Oddi
Pain
Muscle Spasticity
Cholangiography
Liver
Enzymes
Transaminases
Bile Ducts
Analgesics
Hospital Emergency Service
Stomach
Reference Values
Necrosis
Magnetic Resonance Spectroscopy
Pressure
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Citar esto

Berger, Z., Arcos, M., Matamala, F., & Rojas, C. (2017). Cólico biliar inducido por morfina. Revista Medica de Chile, 145(3), 406-409. https://doi.org/10.4067/S0034-98872017000300018
Berger, Zoltán ; Arcos, Mario ; Matamala, Fernanda ; Rojas, Claudia. / Cólico biliar inducido por morfina. En: Revista Medica de Chile. 2017 ; Vol. 145, N.º 3. pp. 406-409.
@article{17ecb372b7044b67b73d0a3ab4884be5,
title = "C{\'o}lico biliar inducido por morfina",
abstract = "Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epi-gastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics. Transaminases elevated from previously normal value to over 1,000 U/L, and returned to the normal level without further treatment after several days. Magnetic resonance cholangiography showed normal fine bile duct, without stones. This transient increase in hepatic enzymes was considered as a consequence of high biliary pressure secondary to morphine-induced spastic contraction of Oddi’s sphincter and a consecutive hepatocellular necrosis.",
keywords = "Morphine, Sphincter of oddi, Sphincter of oddi dysfunction",
author = "Zolt{\'a}n Berger and Mario Arcos and Fernanda Matamala and Claudia Rojas",
year = "2017",
doi = "10.4067/S0034-98872017000300018",
language = "Spanish",
volume = "145",
pages = "406--409",
journal = "Revista Medica de Chile",
issn = "0034-9887",
publisher = "Sociedad Medica de Santiago",
number = "3",

}

Berger, Z, Arcos, M, Matamala, F & Rojas, C 2017, 'Cólico biliar inducido por morfina', Revista Medica de Chile, vol. 145, n.º 3, pp. 406-409. https://doi.org/10.4067/S0034-98872017000300018

Cólico biliar inducido por morfina. / Berger, Zoltán; Arcos, Mario; Matamala, Fernanda; Rojas, Claudia.

En: Revista Medica de Chile, Vol. 145, N.º 3, 2017, p. 406-409.

Resultado de la investigación: Article

TY - JOUR

T1 - Cólico biliar inducido por morfina

AU - Berger, Zoltán

AU - Arcos, Mario

AU - Matamala, Fernanda

AU - Rojas, Claudia

PY - 2017

Y1 - 2017

N2 - Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epi-gastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics. Transaminases elevated from previously normal value to over 1,000 U/L, and returned to the normal level without further treatment after several days. Magnetic resonance cholangiography showed normal fine bile duct, without stones. This transient increase in hepatic enzymes was considered as a consequence of high biliary pressure secondary to morphine-induced spastic contraction of Oddi’s sphincter and a consecutive hepatocellular necrosis.

AB - Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epi-gastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics. Transaminases elevated from previously normal value to over 1,000 U/L, and returned to the normal level without further treatment after several days. Magnetic resonance cholangiography showed normal fine bile duct, without stones. This transient increase in hepatic enzymes was considered as a consequence of high biliary pressure secondary to morphine-induced spastic contraction of Oddi’s sphincter and a consecutive hepatocellular necrosis.

KW - Morphine

KW - Sphincter of oddi

KW - Sphincter of oddi dysfunction

UR - http://www.scopus.com/inward/record.url?scp=85019859271&partnerID=8YFLogxK

U2 - 10.4067/S0034-98872017000300018

DO - 10.4067/S0034-98872017000300018

M3 - Article

AN - SCOPUS:85019859271

VL - 145

SP - 406

EP - 409

JO - Revista Medica de Chile

JF - Revista Medica de Chile

SN - 0034-9887

IS - 3

ER -