Bromodomains in living cells participate in deciphering the histone code

Alejandra Loyola, Genevieve Almouzni

Resultado de la investigación: Review article

29 Citas (Scopus)

Resumen

The bromodomain, a module of ∼110 amino acids, is found in several chromatin-associated proteins, including histone acetyltransferases and chromatin-remodeling factors, and can bind to acetylated lysines. Such post-translational modifications occur mainly in the N-terminal tail of the histone proteins and, in combination with other modifications, are thought to participate in defining a histone code. Recent findings provide a model for how bromodomain-containing proteins participate in the recognition of acetylated histones.

Idioma originalEnglish
Páginas (desde-hasta)279-281
Número de páginas3
PublicaciónTrends in Cell Biology
Volumen14
N.º6
DOI
EstadoPublished - 1 jun 2004

Huella dactilar

Histone Code
Histones
Histone Acetyltransferases
Proteins
Chromatin Assembly and Disassembly
Post Translational Protein Processing
Lysine
Chromatin
Amino Acids

ASJC Scopus subject areas

  • Cell Biology

Citar esto

Loyola, Alejandra ; Almouzni, Genevieve. / Bromodomains in living cells participate in deciphering the histone code. En: Trends in Cell Biology. 2004 ; Vol. 14, N.º 6. pp. 279-281.
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Bromodomains in living cells participate in deciphering the histone code. / Loyola, Alejandra; Almouzni, Genevieve.

En: Trends in Cell Biology, Vol. 14, N.º 6, 01.06.2004, p. 279-281.

Resultado de la investigación: Review article

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