TY - JOUR
T1 - Atypical presentation of pseudomembranous colitis localized in adenomatous polyps
AU - Hernández-Rocha, Cristian
AU - Barra-Carrasco, Jonathan
AU - Guzmán, Ana María
AU - Paredes-Sabja, Daniel
AU - Lezcano, Gabriel
AU - Zoroquiaín, Pablo
AU - Álvarez-Lobos, Manuel
PY - 2013
Y1 - 2013
N2 - The most frequent cause of pseudomembranous colitis is Clostridium difficile (C. difficile) infection. This type of colitis is characterized by an endoscopic pattern of numerous small, yellowish or whitish plaques diffusely distributed, which typically compromises the rectum extending to proximal colon. Occasionally, the pseudomembranes compromise only the transverse or right colon, but their exclusive localization over polyps has not been reported. In this case report we have described a patient with symptoms compatible with C. difficile infection and positive for C. difficile toxigenic culture. Colonoscopy examination showed two small polyps with a whitish surface, and histopathological analysis confirmed them to be pseudomembranes over tubular adenomas. The rest of the colonic mucosa was normal and no other cause was demonstrated. We suggest that this particular distribution might be due to a higher affinity for dysplastic cells such as adenomatous polyps of colon by C. difficile and/or its toxins.
AB - The most frequent cause of pseudomembranous colitis is Clostridium difficile (C. difficile) infection. This type of colitis is characterized by an endoscopic pattern of numerous small, yellowish or whitish plaques diffusely distributed, which typically compromises the rectum extending to proximal colon. Occasionally, the pseudomembranes compromise only the transverse or right colon, but their exclusive localization over polyps has not been reported. In this case report we have described a patient with symptoms compatible with C. difficile infection and positive for C. difficile toxigenic culture. Colonoscopy examination showed two small polyps with a whitish surface, and histopathological analysis confirmed them to be pseudomembranes over tubular adenomas. The rest of the colonic mucosa was normal and no other cause was demonstrated. We suggest that this particular distribution might be due to a higher affinity for dysplastic cells such as adenomatous polyps of colon by C. difficile and/or its toxins.
KW - Adenomatous polyps
KW - Antibiotic-associated colitis
KW - Clostridium difficile
KW - Clostridium difficile infections
KW - Pseudomembranous colitis
UR - http://www.scopus.com/inward/record.url?scp=84873648318&partnerID=8YFLogxK
U2 - 10.3748/wjg.v19.i2.316
DO - 10.3748/wjg.v19.i2.316
M3 - Article
C2 - 23345958
AN - SCOPUS:84873648318
VL - 19
SP - 316
EP - 318
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 2
ER -