Around the Fungal Clock: Recent Advances in the Molecular Study of Circadian Clocks in Neurospora and Other Fungi

Alejandro Montenegro-Montero, Paulo Canessa, Luis F. Larrondo

Resultado de la investigación: Conference contribution

24 Citas (Scopus)

Resumen

Night follows day and as a consequence, organisms have evolved molecular machineries that allow them to anticipate and respond to the many changes that accompany these transitions. Circadian clocks are precise yet plastic pacemakers that allow the temporal organization of a plethora of biological process. Circadian clocks are widespread across the tree of life and while their exact molecular components differ among phyla, they tend to share common design principles. In this review, we discuss the circadian system of the filamentous fungus Neurospora crassa. Historically, this fungus has served a key role in the genetic and molecular dissection of circadian clocks, aiding in their detailed mechanistic understanding. Recent studies have provided new insights into the daily molecular dynamics that constitute the Neurospora circadian oscillator, some of which have questioned traditional paradigms describing timekeeping mechanisms in eukaryotes. In addition, recent reports support the idea of a dynamic network of transcription factors underlying the rhythmicity of thousands of genes in Neurospora, many of which oscillate only under specific conditions. Besides Neurospora, which harbors the best characterized circadian system among filamentous fungi, the recent characterization of the circadian system of the plant-pathogenic fungus Botrytis cinerea has provided additional insights into the physiological impact of the clock and potential additional functions of clock proteins in fungi. Finally, we speculate on the presence of FRQ or FRQ-like proteins in diverse fungal lineages.

Idioma originalEnglish
Título de la publicación alojadaAdvances in Genetics, 2015
EditorialAcademic Press Inc.
Páginas107-184
Número de páginas78
ISBN (versión impresa)9780128040140
DOI
EstadoPublished - 1 ene 2015

Serie de la publicación

NombreAdvances in Genetics
Volumen92
ISSN (versión impresa)0065-2660

Huella dactilar

Neurospora
Circadian Clocks
Fungi
Botrytis
Biological Phenomena
Neurospora crassa
Periodicity
Molecular Dynamics Simulation
Eukaryota
Plastics
Dissection
Molecular Biology
Proteins
Transcription Factors
Genes

ASJC Scopus subject areas

  • Genetics

Citar esto

Montenegro-Montero, A., Canessa, P., & Larrondo, L. F. (2015). Around the Fungal Clock: Recent Advances in the Molecular Study of Circadian Clocks in Neurospora and Other Fungi. En Advances in Genetics, 2015 (pp. 107-184). (Advances in Genetics; Vol. 92). Academic Press Inc.. https://doi.org/10.1016/bs.adgen.2015.09.003
Montenegro-Montero, Alejandro ; Canessa, Paulo ; Larrondo, Luis F. / Around the Fungal Clock : Recent Advances in the Molecular Study of Circadian Clocks in Neurospora and Other Fungi. Advances in Genetics, 2015. Academic Press Inc., 2015. pp. 107-184 (Advances in Genetics).
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Montenegro-Montero, A, Canessa, P & Larrondo, LF 2015, Around the Fungal Clock: Recent Advances in the Molecular Study of Circadian Clocks in Neurospora and Other Fungi. En Advances in Genetics, 2015. Advances in Genetics, vol. 92, Academic Press Inc., pp. 107-184. https://doi.org/10.1016/bs.adgen.2015.09.003

Around the Fungal Clock : Recent Advances in the Molecular Study of Circadian Clocks in Neurospora and Other Fungi. / Montenegro-Montero, Alejandro; Canessa, Paulo; Larrondo, Luis F.

Advances in Genetics, 2015. Academic Press Inc., 2015. p. 107-184 (Advances in Genetics; Vol. 92).

Resultado de la investigación: Conference contribution

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Montenegro-Montero A, Canessa P, Larrondo LF. Around the Fungal Clock: Recent Advances in the Molecular Study of Circadian Clocks in Neurospora and Other Fungi. En Advances in Genetics, 2015. Academic Press Inc. 2015. p. 107-184. (Advances in Genetics). https://doi.org/10.1016/bs.adgen.2015.09.003