Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities 06 Biological Sciences 0605 Microbiology 11 Medical and Health Sciences 1117 Public Health and Health Services

David A. Montero, Carolina Arellano, Mirka Pardo, Rosa Vera, Ricardo Gálvez, Marcela Cifuentes, Mariá A. Berasain, Marisol Gómez, Claudio Ramírez, Roberto M. Vidal

Resultado de la investigación: Article

1 Cita (Scopus)

Resumen

Background: Healthcare-associated infections (HAIs) have a major impact on public health worldwide. Particularly, hospital surfaces contaminated with bacterial pathogens are often the origin of both sporadic cases and outbreaks of HAIs. It has been demonstrated that copper surfaces reduce the microbial burden of high touch surfaces in the hospital environment. Here we report the antimicrobial characterization of a novel composite coating with embedded copper particles, named Copper Armour™. Methods: The Copper Armour™ bactericidal activity was evaluated in in vitro assays against several bacterial pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli O157:H7 and Listeria monocytogenes. Additionally, its antimicrobial properties were also evaluated in a pilot study over a nine-week period at an adult intensive care unit. For this, four high touch surfaces, including bed rails, overbed table, bedside table and IV Pole, were coated with Cooper Armour™, and its microbial burden was determined over a nine-week period. Results: Copper Armour™ coated samples showed an in vitro reduction in bacterial burden of > 99.9% compared to control samples. Moreover, pilot study results indicate that Copper Armour™ significantly reduces the level of microbial contamination on high-touch surfaces in the hospital environment, as compared with standard surfaces. Conclusions: Based on its antimicrobial properties, Copper Armour™ is a novel self-sanitizing coating that exhibits bactericidal activity against important human pathogens and significantly reduces the microbial burden of hospital surfaces. This composite could be used as a self-sanitizing coating to complement infection control strategies in healthcare facilities.

Idioma originalEnglish
Número de artículo3
PublicaciónAntimicrobial Resistance and Infection Control
Volumen8
N.º1
DOI
EstadoPublished - 5 ene 2019
Publicado de forma externa

Huella dactilar

Biological Science Disciplines
Microbiology
Health Services
Copper
Public Health
Delivery of Health Care
Health
Touch
Cross Infection
Escherichia coli O157
Listeria monocytogenes
Infection Control
Pseudomonas aeruginosa
Disease Outbreaks
Intensive Care Units
Staphylococcus aureus

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

Citar esto

Montero, David A. ; Arellano, Carolina ; Pardo, Mirka ; Vera, Rosa ; Gálvez, Ricardo ; Cifuentes, Marcela ; Berasain, Mariá A. ; Gómez, Marisol ; Ramírez, Claudio ; Vidal, Roberto M. / Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities 06 Biological Sciences 0605 Microbiology 11 Medical and Health Sciences 1117 Public Health and Health Services. En: Antimicrobial Resistance and Infection Control. 2019 ; Vol. 8, N.º 1.
@article{b7eb4ef0c58d4d6da3bd6989bca61fcd,
title = "Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities 06 Biological Sciences 0605 Microbiology 11 Medical and Health Sciences 1117 Public Health and Health Services",
abstract = "Background: Healthcare-associated infections (HAIs) have a major impact on public health worldwide. Particularly, hospital surfaces contaminated with bacterial pathogens are often the origin of both sporadic cases and outbreaks of HAIs. It has been demonstrated that copper surfaces reduce the microbial burden of high touch surfaces in the hospital environment. Here we report the antimicrobial characterization of a novel composite coating with embedded copper particles, named Copper Armour™. Methods: The Copper Armour™ bactericidal activity was evaluated in in vitro assays against several bacterial pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli O157:H7 and Listeria monocytogenes. Additionally, its antimicrobial properties were also evaluated in a pilot study over a nine-week period at an adult intensive care unit. For this, four high touch surfaces, including bed rails, overbed table, bedside table and IV Pole, were coated with Cooper Armour™, and its microbial burden was determined over a nine-week period. Results: Copper Armour™ coated samples showed an in vitro reduction in bacterial burden of > 99.9{\%} compared to control samples. Moreover, pilot study results indicate that Copper Armour™ significantly reduces the level of microbial contamination on high-touch surfaces in the hospital environment, as compared with standard surfaces. Conclusions: Based on its antimicrobial properties, Copper Armour™ is a novel self-sanitizing coating that exhibits bactericidal activity against important human pathogens and significantly reduces the microbial burden of hospital surfaces. This composite could be used as a self-sanitizing coating to complement infection control strategies in healthcare facilities.",
keywords = "Antimicrobial copper, Copper-based composite, Healthcare-associated infections, High-touch surfaces, Self-sanitizing coating",
author = "Montero, {David A.} and Carolina Arellano and Mirka Pardo and Rosa Vera and Ricardo G{\'a}lvez and Marcela Cifuentes and Berasain, {Mari{\'a} A.} and Marisol G{\'o}mez and Claudio Ram{\'i}rez and Vidal, {Roberto M.}",
year = "2019",
month = "1",
day = "5",
doi = "10.1186/s13756-018-0456-4",
language = "English",
volume = "8",
journal = "Antimicrobial Resistance and Infection Control",
issn = "2047-2994",
publisher = "BioMed Central",
number = "1",

}

Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities 06 Biological Sciences 0605 Microbiology 11 Medical and Health Sciences 1117 Public Health and Health Services. / Montero, David A.; Arellano, Carolina; Pardo, Mirka; Vera, Rosa; Gálvez, Ricardo; Cifuentes, Marcela; Berasain, Mariá A.; Gómez, Marisol; Ramírez, Claudio; Vidal, Roberto M.

En: Antimicrobial Resistance and Infection Control, Vol. 8, N.º 1, 3, 05.01.2019.

Resultado de la investigación: Article

TY - JOUR

T1 - Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities 06 Biological Sciences 0605 Microbiology 11 Medical and Health Sciences 1117 Public Health and Health Services

AU - Montero, David A.

AU - Arellano, Carolina

AU - Pardo, Mirka

AU - Vera, Rosa

AU - Gálvez, Ricardo

AU - Cifuentes, Marcela

AU - Berasain, Mariá A.

AU - Gómez, Marisol

AU - Ramírez, Claudio

AU - Vidal, Roberto M.

PY - 2019/1/5

Y1 - 2019/1/5

N2 - Background: Healthcare-associated infections (HAIs) have a major impact on public health worldwide. Particularly, hospital surfaces contaminated with bacterial pathogens are often the origin of both sporadic cases and outbreaks of HAIs. It has been demonstrated that copper surfaces reduce the microbial burden of high touch surfaces in the hospital environment. Here we report the antimicrobial characterization of a novel composite coating with embedded copper particles, named Copper Armour™. Methods: The Copper Armour™ bactericidal activity was evaluated in in vitro assays against several bacterial pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli O157:H7 and Listeria monocytogenes. Additionally, its antimicrobial properties were also evaluated in a pilot study over a nine-week period at an adult intensive care unit. For this, four high touch surfaces, including bed rails, overbed table, bedside table and IV Pole, were coated with Cooper Armour™, and its microbial burden was determined over a nine-week period. Results: Copper Armour™ coated samples showed an in vitro reduction in bacterial burden of > 99.9% compared to control samples. Moreover, pilot study results indicate that Copper Armour™ significantly reduces the level of microbial contamination on high-touch surfaces in the hospital environment, as compared with standard surfaces. Conclusions: Based on its antimicrobial properties, Copper Armour™ is a novel self-sanitizing coating that exhibits bactericidal activity against important human pathogens and significantly reduces the microbial burden of hospital surfaces. This composite could be used as a self-sanitizing coating to complement infection control strategies in healthcare facilities.

AB - Background: Healthcare-associated infections (HAIs) have a major impact on public health worldwide. Particularly, hospital surfaces contaminated with bacterial pathogens are often the origin of both sporadic cases and outbreaks of HAIs. It has been demonstrated that copper surfaces reduce the microbial burden of high touch surfaces in the hospital environment. Here we report the antimicrobial characterization of a novel composite coating with embedded copper particles, named Copper Armour™. Methods: The Copper Armour™ bactericidal activity was evaluated in in vitro assays against several bacterial pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli O157:H7 and Listeria monocytogenes. Additionally, its antimicrobial properties were also evaluated in a pilot study over a nine-week period at an adult intensive care unit. For this, four high touch surfaces, including bed rails, overbed table, bedside table and IV Pole, were coated with Cooper Armour™, and its microbial burden was determined over a nine-week period. Results: Copper Armour™ coated samples showed an in vitro reduction in bacterial burden of > 99.9% compared to control samples. Moreover, pilot study results indicate that Copper Armour™ significantly reduces the level of microbial contamination on high-touch surfaces in the hospital environment, as compared with standard surfaces. Conclusions: Based on its antimicrobial properties, Copper Armour™ is a novel self-sanitizing coating that exhibits bactericidal activity against important human pathogens and significantly reduces the microbial burden of hospital surfaces. This composite could be used as a self-sanitizing coating to complement infection control strategies in healthcare facilities.

KW - Antimicrobial copper

KW - Copper-based composite

KW - Healthcare-associated infections

KW - High-touch surfaces

KW - Self-sanitizing coating

UR - http://www.scopus.com/inward/record.url?scp=85059589203&partnerID=8YFLogxK

U2 - 10.1186/s13756-018-0456-4

DO - 10.1186/s13756-018-0456-4

M3 - Article

VL - 8

JO - Antimicrobial Resistance and Infection Control

JF - Antimicrobial Resistance and Infection Control

SN - 2047-2994

IS - 1

M1 - 3

ER -