Antigen engineering in Yeast: Synthesis and assembly of hybrid hepatitis b surface antigen-herpes simplex 1 gd particles

Pablo Valenzuela, Doris Coit, M. Angelica Medina-Selby, Ching H. Kuo, Gary Van Nest, Rae Lyn Burke, Paulina Bull, Mickey S. Urdea, Pierre V. Graves

Resultado de la investigación: Contribución a una revistaArtículo

67 Citas (Scopus)

Resumen

A new approach for antigen presentation and polyvalent vaccines is tested. The idea is to recombine the gene of a second immunogen with that of hepatitis B surface antigen so that the second immunogen is assembled into, and presented on the surface of the HBsAg particle. We describe here the synthesis and assembly in yeast of a model hybrid particle containing both, hepatitis B virus and herpes simplex virus surface antigens.

Idioma originalInglés
Páginas (desde-hasta)323-326
Número de páginas4
PublicaciónBio/Technology
Volumen3
N.º4
DOI
EstadoPublicada - 1 ene 1985

Áreas temáticas de ASJC Scopus

  • Biotecnología

Huella Profundice en los temas de investigación de 'Antigen engineering in Yeast: Synthesis and assembly of hybrid hepatitis b surface antigen-herpes simplex 1 gd particles'. En conjunto forman una huella única.

  • Citar esto

    Valenzuela, P., Coit, D., Medina-Selby, M. A., Kuo, C. H., Van Nest, G., Burke, R. L., Bull, P., Urdea, M. S., & Graves, P. V. (1985). Antigen engineering in Yeast: Synthesis and assembly of hybrid hepatitis b surface antigen-herpes simplex 1 gd particles. Bio/Technology, 3(4), 323-326. https://doi.org/10.1038/nbt0485-323