Anticoagulation Management With Coumarinic Drugs in Chilean Patients

Elena Nieto, Marcelo Suarez, Ángela Roco, Juan Carlos Rubilar, Francisca Tamayo, Mario Rojo, Gabriel Verón, Juliana Sepúlveda, Fanny Mejías, Patricio Salas, María Góngora, Patricio Andrade, Alicia Canales, Jorge Carabantes, Daniela Cruz, Emma Contreras, Daniela Pavez, Paulina Charo, Gabriela Bravo, Juan Calderón & 3 otros Carlos Gallardo, Patricia Vega, Luis A. Quiñones

Resultado de la investigación: Article

Resumen

Warfarin and acenocoumarol are used in various cardiovascular disorders to improve the prognosis of patients with thromboembolic disease. However, there is a lack of substantial efficacy and safety data on antithrombotic prophylaxis in several countries, particularly in Latin America. The aim of this study was to provide information about the efficacy of anticoagulants in Chilean patients. Data were collected from databases of the Western Metropolitan Health Service, Santiago, Chile. We identified 6280 records of patients receiving anticoagulant treatment. The three most common diagnoses were rhythm disorder (43.7%), venous thrombosis (22%), and valvular prosthesis (10.7%). The majority of patients (98.5%) received acenocoumarol while 1.5% of patients received warfarin, at weekly therapeutic doses of 13.6 mg and 30.4 mg, respectively. For total diagnoses, the median time in the therapeutic range was 50%. However, better results, 66.7%, were observed when a telemedicine strategy was used only in Santiago Province. Our findings emphasize that in Chile, where the number of patients receiving anticoagulant treatment increases every year, telemedicine, by committed teams, improves the use of oral anticoagulants and is able to increase quality indicators of anticoagulant treatment care.

Idioma originalEnglish
PublicaciónClinical and Applied Thrombosis/Hemostasis
Volumen25
DOI
EstadoPublished - 14 mar 2019
Publicado de forma externa

Huella dactilar

Anticoagulants
Acenocoumarol
Pharmaceutical Preparations
Telemedicine
Chile
Warfarin
Therapeutics
Latin America
Venous Thrombosis
Prostheses and Implants
Health Services
Databases
Safety

ASJC Scopus subject areas

  • Hematology

Citar esto

Nieto, E., Suarez, M., Roco, Á., Rubilar, J. C., Tamayo, F., Rojo, M., ... Quiñones, L. A. (2019). Anticoagulation Management With Coumarinic Drugs in Chilean Patients. Clinical and Applied Thrombosis/Hemostasis, 25. https://doi.org/10.1177/1076029619834342
Nieto, Elena ; Suarez, Marcelo ; Roco, Ángela ; Rubilar, Juan Carlos ; Tamayo, Francisca ; Rojo, Mario ; Verón, Gabriel ; Sepúlveda, Juliana ; Mejías, Fanny ; Salas, Patricio ; Góngora, María ; Andrade, Patricio ; Canales, Alicia ; Carabantes, Jorge ; Cruz, Daniela ; Contreras, Emma ; Pavez, Daniela ; Charo, Paulina ; Bravo, Gabriela ; Calderón, Juan ; Gallardo, Carlos ; Vega, Patricia ; Quiñones, Luis A. / Anticoagulation Management With Coumarinic Drugs in Chilean Patients. En: Clinical and Applied Thrombosis/Hemostasis. 2019 ; Vol. 25.
@article{c8a924b05aa043a59925cf14dc7d1bef,
title = "Anticoagulation Management With Coumarinic Drugs in Chilean Patients",
abstract = "Warfarin and acenocoumarol are used in various cardiovascular disorders to improve the prognosis of patients with thromboembolic disease. However, there is a lack of substantial efficacy and safety data on antithrombotic prophylaxis in several countries, particularly in Latin America. The aim of this study was to provide information about the efficacy of anticoagulants in Chilean patients. Data were collected from databases of the Western Metropolitan Health Service, Santiago, Chile. We identified 6280 records of patients receiving anticoagulant treatment. The three most common diagnoses were rhythm disorder (43.7{\%}), venous thrombosis (22{\%}), and valvular prosthesis (10.7{\%}). The majority of patients (98.5{\%}) received acenocoumarol while 1.5{\%} of patients received warfarin, at weekly therapeutic doses of 13.6 mg and 30.4 mg, respectively. For total diagnoses, the median time in the therapeutic range was 50{\%}. However, better results, 66.7{\%}, were observed when a telemedicine strategy was used only in Santiago Province. Our findings emphasize that in Chile, where the number of patients receiving anticoagulant treatment increases every year, telemedicine, by committed teams, improves the use of oral anticoagulants and is able to increase quality indicators of anticoagulant treatment care.",
keywords = "acenocoumarol, safety, telemedicine, thrombosis, warfarin",
author = "Elena Nieto and Marcelo Suarez and {\'A}ngela Roco and Rubilar, {Juan Carlos} and Francisca Tamayo and Mario Rojo and Gabriel Ver{\'o}n and Juliana Sep{\'u}lveda and Fanny Mej{\'i}as and Patricio Salas and Mar{\'i}a G{\'o}ngora and Patricio Andrade and Alicia Canales and Jorge Carabantes and Daniela Cruz and Emma Contreras and Daniela Pavez and Paulina Charo and Gabriela Bravo and Juan Calder{\'o}n and Carlos Gallardo and Patricia Vega and Qui{\~n}ones, {Luis A.}",
year = "2019",
month = "3",
day = "14",
doi = "10.1177/1076029619834342",
language = "English",
volume = "25",
journal = "Clinical and Applied Thrombosis/Hemostasis",
issn = "1076-0296",
publisher = "SAGE Publications Inc.",

}

Nieto, E, Suarez, M, Roco, Á, Rubilar, JC, Tamayo, F, Rojo, M, Verón, G, Sepúlveda, J, Mejías, F, Salas, P, Góngora, M, Andrade, P, Canales, A, Carabantes, J, Cruz, D, Contreras, E, Pavez, D, Charo, P, Bravo, G, Calderón, J, Gallardo, C, Vega, P & Quiñones, LA 2019, 'Anticoagulation Management With Coumarinic Drugs in Chilean Patients', Clinical and Applied Thrombosis/Hemostasis, vol. 25. https://doi.org/10.1177/1076029619834342

Anticoagulation Management With Coumarinic Drugs in Chilean Patients. / Nieto, Elena; Suarez, Marcelo; Roco, Ángela; Rubilar, Juan Carlos; Tamayo, Francisca; Rojo, Mario; Verón, Gabriel; Sepúlveda, Juliana; Mejías, Fanny; Salas, Patricio; Góngora, María; Andrade, Patricio; Canales, Alicia; Carabantes, Jorge; Cruz, Daniela; Contreras, Emma; Pavez, Daniela; Charo, Paulina; Bravo, Gabriela; Calderón, Juan; Gallardo, Carlos; Vega, Patricia; Quiñones, Luis A.

En: Clinical and Applied Thrombosis/Hemostasis, Vol. 25, 14.03.2019.

Resultado de la investigación: Article

TY - JOUR

T1 - Anticoagulation Management With Coumarinic Drugs in Chilean Patients

AU - Nieto, Elena

AU - Suarez, Marcelo

AU - Roco, Ángela

AU - Rubilar, Juan Carlos

AU - Tamayo, Francisca

AU - Rojo, Mario

AU - Verón, Gabriel

AU - Sepúlveda, Juliana

AU - Mejías, Fanny

AU - Salas, Patricio

AU - Góngora, María

AU - Andrade, Patricio

AU - Canales, Alicia

AU - Carabantes, Jorge

AU - Cruz, Daniela

AU - Contreras, Emma

AU - Pavez, Daniela

AU - Charo, Paulina

AU - Bravo, Gabriela

AU - Calderón, Juan

AU - Gallardo, Carlos

AU - Vega, Patricia

AU - Quiñones, Luis A.

PY - 2019/3/14

Y1 - 2019/3/14

N2 - Warfarin and acenocoumarol are used in various cardiovascular disorders to improve the prognosis of patients with thromboembolic disease. However, there is a lack of substantial efficacy and safety data on antithrombotic prophylaxis in several countries, particularly in Latin America. The aim of this study was to provide information about the efficacy of anticoagulants in Chilean patients. Data were collected from databases of the Western Metropolitan Health Service, Santiago, Chile. We identified 6280 records of patients receiving anticoagulant treatment. The three most common diagnoses were rhythm disorder (43.7%), venous thrombosis (22%), and valvular prosthesis (10.7%). The majority of patients (98.5%) received acenocoumarol while 1.5% of patients received warfarin, at weekly therapeutic doses of 13.6 mg and 30.4 mg, respectively. For total diagnoses, the median time in the therapeutic range was 50%. However, better results, 66.7%, were observed when a telemedicine strategy was used only in Santiago Province. Our findings emphasize that in Chile, where the number of patients receiving anticoagulant treatment increases every year, telemedicine, by committed teams, improves the use of oral anticoagulants and is able to increase quality indicators of anticoagulant treatment care.

AB - Warfarin and acenocoumarol are used in various cardiovascular disorders to improve the prognosis of patients with thromboembolic disease. However, there is a lack of substantial efficacy and safety data on antithrombotic prophylaxis in several countries, particularly in Latin America. The aim of this study was to provide information about the efficacy of anticoagulants in Chilean patients. Data were collected from databases of the Western Metropolitan Health Service, Santiago, Chile. We identified 6280 records of patients receiving anticoagulant treatment. The three most common diagnoses were rhythm disorder (43.7%), venous thrombosis (22%), and valvular prosthesis (10.7%). The majority of patients (98.5%) received acenocoumarol while 1.5% of patients received warfarin, at weekly therapeutic doses of 13.6 mg and 30.4 mg, respectively. For total diagnoses, the median time in the therapeutic range was 50%. However, better results, 66.7%, were observed when a telemedicine strategy was used only in Santiago Province. Our findings emphasize that in Chile, where the number of patients receiving anticoagulant treatment increases every year, telemedicine, by committed teams, improves the use of oral anticoagulants and is able to increase quality indicators of anticoagulant treatment care.

KW - acenocoumarol

KW - safety

KW - telemedicine

KW - thrombosis

KW - warfarin

UR - http://www.scopus.com/inward/record.url?scp=85063216864&partnerID=8YFLogxK

U2 - 10.1177/1076029619834342

DO - 10.1177/1076029619834342

M3 - Article

VL - 25

JO - Clinical and Applied Thrombosis/Hemostasis

JF - Clinical and Applied Thrombosis/Hemostasis

SN - 1076-0296

ER -