TY - JOUR
T1 - Antibacterial potential assessment of Nalca (Gunnera tinctoria Mol.) ethanolic extracts
AU - Velásquez, Patricia
AU - Riquelme, Karla
AU - Leyton, Felipe
AU - Giordano, Ady
AU - Gómez, Miguel
AU - Montenegro, Gloria
N1 - Publisher Copyright:
© 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021
Y1 - 2021
N2 - Nalca is an edible rhubarb-type plant from the southern of Chile; with studies focussing on petiole chemical and biological properties. This work evaluated for the first time the antibacterial capacities of three organs of nalca against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. Petiole (P), root (R) and flower (F) ethanolic extracts at three different concentrations (25, 50, 100 mg/mL) were evaluated by means of agar diffusion assay and MIC. The result showed that antibacterial activities are bacteria and concentration dependent, with root having the highest antimicrobial activity of the organs plant studied. Compared to commercial antibiotics, nalca extracts show promising control over Ps. aeruginosa. The main polyphenolics of the extracts were identified by UPLC–MS/MS, observing for the first time caffeic, coumaric and gallic acids presence in all samples, with quercetin and rutin determined in petiole and flower extracts only. Our results contribute to better understanding of nalca attributes as potential source of antibacterial compounds to be used in nutraceutical, cosmetic and food industry.
AB - Nalca is an edible rhubarb-type plant from the southern of Chile; with studies focussing on petiole chemical and biological properties. This work evaluated for the first time the antibacterial capacities of three organs of nalca against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. Petiole (P), root (R) and flower (F) ethanolic extracts at three different concentrations (25, 50, 100 mg/mL) were evaluated by means of agar diffusion assay and MIC. The result showed that antibacterial activities are bacteria and concentration dependent, with root having the highest antimicrobial activity of the organs plant studied. Compared to commercial antibiotics, nalca extracts show promising control over Ps. aeruginosa. The main polyphenolics of the extracts were identified by UPLC–MS/MS, observing for the first time caffeic, coumaric and gallic acids presence in all samples, with quercetin and rutin determined in petiole and flower extracts only. Our results contribute to better understanding of nalca attributes as potential source of antibacterial compounds to be used in nutraceutical, cosmetic and food industry.
KW - agar diffusion
KW - antimicrobial activity
KW - bioactive extracts
KW - Gunnera tinctoriaMol
KW - minimum inhibitory concentration
UR - http://www.scopus.com/inward/record.url?scp=85086939097&partnerID=8YFLogxK
U2 - 10.1080/14786419.2020.1777118
DO - 10.1080/14786419.2020.1777118
M3 - Article
C2 - 32543964
AN - SCOPUS:85086939097
SN - 1478-6419
VL - 35
SP - 5425
EP - 5428
JO - Natural Product Research
JF - Natural Product Research
IS - 23
ER -