Acute respiratory distress syndrome resulting from inhalation of powdered copper

Alejandro Donoso, Pablo Cruces, Jorge Camacho, Juan Carlos Ríos, Enrique Paris, Juan Jose Mieres

Resultado de la investigación: Article

5 Citas (Scopus)

Resumen

Background. Copper is an essential element. Poisoning with elemental copper is infrequent and manifestations rarely include the ones that our case presented. Case report. A previously healthy 2-year-old female patient unintentionally inhaled copper dust, developed respiratory failure a few hours later, and required mechanical ventilation. On hospital day three, the patient developed acute respiratory distress syndrome and was treated with high-frequency oscillatory ventilation for six days. She also developed hemolytic anemia, liver failure, oliguric renal failure, and evidence of acute tubular injury. During her stay in the intensive care unit she received inotropic support, packed red cells transfusion, and diuretics. A sample of bronchoalveolar lavage showed macrophages that stained positive for copper. Serum and urine copper concentrations were within the normal range after several days. Extubation was successfully achieved after two weeks and the patient was discharged on day 30 without sequelae. This is the first report of acute respiratory distress syndrome secondary to copper aspiration in a pediatric patient. Conclusion. To our knowledge, this is the first case reported of acute respiratory distress syndrome secondary to elemental copper aspiration. It is important to the clinician to be aware of acute respiratory distress syndrome as a differential diagnosis to copper aspiration by treating the patient aggressively in an adequate clinical setting.

Idioma originalEnglish
Páginas (desde-hasta)714-716
Número de páginas3
PublicaciónClinical Toxicology
Volumen45
N.º6
DOI
EstadoPublished - sep 2007

Huella dactilar

Adult Respiratory Distress Syndrome
Inhalation
Copper
High-Frequency Ventilation
Intensive care units
Pediatrics
Macrophages
Hemolytic Anemia
Liver Failure
Bronchoalveolar Lavage
Dust
Artificial Respiration
Diuretics
Acute Kidney Injury
Respiratory Insufficiency
Liver
Poisoning
Ventilation
Intensive Care Units
Reference Values

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Toxicology
  • Medicine(all)

Citar esto

Donoso, Alejandro ; Cruces, Pablo ; Camacho, Jorge ; Ríos, Juan Carlos ; Paris, Enrique ; Mieres, Juan Jose. / Acute respiratory distress syndrome resulting from inhalation of powdered copper. En: Clinical Toxicology. 2007 ; Vol. 45, N.º 6. pp. 714-716.
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abstract = "Background. Copper is an essential element. Poisoning with elemental copper is infrequent and manifestations rarely include the ones that our case presented. Case report. A previously healthy 2-year-old female patient unintentionally inhaled copper dust, developed respiratory failure a few hours later, and required mechanical ventilation. On hospital day three, the patient developed acute respiratory distress syndrome and was treated with high-frequency oscillatory ventilation for six days. She also developed hemolytic anemia, liver failure, oliguric renal failure, and evidence of acute tubular injury. During her stay in the intensive care unit she received inotropic support, packed red cells transfusion, and diuretics. A sample of bronchoalveolar lavage showed macrophages that stained positive for copper. Serum and urine copper concentrations were within the normal range after several days. Extubation was successfully achieved after two weeks and the patient was discharged on day 30 without sequelae. This is the first report of acute respiratory distress syndrome secondary to copper aspiration in a pediatric patient. Conclusion. To our knowledge, this is the first case reported of acute respiratory distress syndrome secondary to elemental copper aspiration. It is important to the clinician to be aware of acute respiratory distress syndrome as a differential diagnosis to copper aspiration by treating the patient aggressively in an adequate clinical setting.",
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Acute respiratory distress syndrome resulting from inhalation of powdered copper. / Donoso, Alejandro; Cruces, Pablo; Camacho, Jorge; Ríos, Juan Carlos; Paris, Enrique; Mieres, Juan Jose.

En: Clinical Toxicology, Vol. 45, N.º 6, 09.2007, p. 714-716.

Resultado de la investigación: Article

TY - JOUR

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AU - Cruces, Pablo

AU - Camacho, Jorge

AU - Ríos, Juan Carlos

AU - Paris, Enrique

AU - Mieres, Juan Jose

PY - 2007/9

Y1 - 2007/9

N2 - Background. Copper is an essential element. Poisoning with elemental copper is infrequent and manifestations rarely include the ones that our case presented. Case report. A previously healthy 2-year-old female patient unintentionally inhaled copper dust, developed respiratory failure a few hours later, and required mechanical ventilation. On hospital day three, the patient developed acute respiratory distress syndrome and was treated with high-frequency oscillatory ventilation for six days. She also developed hemolytic anemia, liver failure, oliguric renal failure, and evidence of acute tubular injury. During her stay in the intensive care unit she received inotropic support, packed red cells transfusion, and diuretics. A sample of bronchoalveolar lavage showed macrophages that stained positive for copper. Serum and urine copper concentrations were within the normal range after several days. Extubation was successfully achieved after two weeks and the patient was discharged on day 30 without sequelae. This is the first report of acute respiratory distress syndrome secondary to copper aspiration in a pediatric patient. Conclusion. To our knowledge, this is the first case reported of acute respiratory distress syndrome secondary to elemental copper aspiration. It is important to the clinician to be aware of acute respiratory distress syndrome as a differential diagnosis to copper aspiration by treating the patient aggressively in an adequate clinical setting.

AB - Background. Copper is an essential element. Poisoning with elemental copper is infrequent and manifestations rarely include the ones that our case presented. Case report. A previously healthy 2-year-old female patient unintentionally inhaled copper dust, developed respiratory failure a few hours later, and required mechanical ventilation. On hospital day three, the patient developed acute respiratory distress syndrome and was treated with high-frequency oscillatory ventilation for six days. She also developed hemolytic anemia, liver failure, oliguric renal failure, and evidence of acute tubular injury. During her stay in the intensive care unit she received inotropic support, packed red cells transfusion, and diuretics. A sample of bronchoalveolar lavage showed macrophages that stained positive for copper. Serum and urine copper concentrations were within the normal range after several days. Extubation was successfully achieved after two weeks and the patient was discharged on day 30 without sequelae. This is the first report of acute respiratory distress syndrome secondary to copper aspiration in a pediatric patient. Conclusion. To our knowledge, this is the first case reported of acute respiratory distress syndrome secondary to elemental copper aspiration. It is important to the clinician to be aware of acute respiratory distress syndrome as a differential diagnosis to copper aspiration by treating the patient aggressively in an adequate clinical setting.

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