Acompanhamento de mulheres com células escamosas atípicas não pode excluir lesão intraepitelial de alto grau (ASC-H)

Fanny López-Alegría, Dino Soares De Lorenzi, Orlando Poblete Quezada

Resultado de la investigación: Article

4 Citas (Scopus)

Resumen

Context and Objective: The concept that the presence of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H) was introduced in the 2001 Bethesda System of cervical cytology classification. This nomenclature defines cervical cancer precursor lesions. The objective of this study was to investigate the colpocytological-histological results from a three-year follow-up conducted on a cohort of women with reports of ASC-H who were attended during 2005-2006 at clinics of the Southern Metropolitan Healthcare Service of Santiago, Chile. Design and Setting: Prospective cohort study at primary healthcare clinics in Santiago, Chile. Methods: Colpocytological-histological follow-up was conducted over a three-year period on 92 women with cytological reports of ASC-H who were attended at primary healthcare clinics during 2005-2006. Results: At the end of the follow-up period, high-grade lesions were evaluated and the following outcomes were observed: seven women presented invasive cancer (7.6%), 49 presented high-grade lesions (53.3%), 26 presented low-grade lesions (28.2%) and 10 presented normal results (10.9%). The "Conditional Probabilities Tree Diagram" was used to show the results from tests and the times of lesion detection. It demonstrated that, after a first report of ASC-H, clinical management needed to be interventionist. Conclusion: The follow-up on our cohort of women showed that the majority of uncertain ASC-H diagnoses (82.6%) had abnormal colposcopic results and that during the follow-up using ASC-H smears, two out of every three women developed high-grade lesions.

Idioma originalPortuguese
Páginas (desde-hasta)15-22
Número de páginas8
PublicaciónSao Paulo Medical Journal
Volumen132
N.º1
DOI
EstadoPublished - 2014

Huella dactilar

Chile
Primary Health Care
Terminology
Uterine Cervical Neoplasms
Cell Biology
Cohort Studies
Squamous Intraepithelial Lesions of the Cervix
Atypical Squamous Cells of the Cervix
Prospective Studies
Delivery of Health Care
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Citar esto

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title = "Acompanhamento de mulheres com c{\'e}lulas escamosas at{\'i}picas n{\~a}o pode excluir les{\~a}o intraepitelial de alto grau (ASC-H)",
abstract = "Context and Objective: The concept that the presence of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H) was introduced in the 2001 Bethesda System of cervical cytology classification. This nomenclature defines cervical cancer precursor lesions. The objective of this study was to investigate the colpocytological-histological results from a three-year follow-up conducted on a cohort of women with reports of ASC-H who were attended during 2005-2006 at clinics of the Southern Metropolitan Healthcare Service of Santiago, Chile. Design and Setting: Prospective cohort study at primary healthcare clinics in Santiago, Chile. Methods: Colpocytological-histological follow-up was conducted over a three-year period on 92 women with cytological reports of ASC-H who were attended at primary healthcare clinics during 2005-2006. Results: At the end of the follow-up period, high-grade lesions were evaluated and the following outcomes were observed: seven women presented invasive cancer (7.6{\%}), 49 presented high-grade lesions (53.3{\%}), 26 presented low-grade lesions (28.2{\%}) and 10 presented normal results (10.9{\%}). The {"}Conditional Probabilities Tree Diagram{"} was used to show the results from tests and the times of lesion detection. It demonstrated that, after a first report of ASC-H, clinical management needed to be interventionist. Conclusion: The follow-up on our cohort of women showed that the majority of uncertain ASC-H diagnoses (82.6{\%}) had abnormal colposcopic results and that during the follow-up using ASC-H smears, two out of every three women developed high-grade lesions.",
keywords = "Biopsy, Follow-up studies, Neoplasms squamous cell, Uterine cervical neoplasms, Vaginal smears",
author = "Fanny L{\'o}pez-Alegr{\'i}a and {De Lorenzi}, {Dino Soares} and Quezada, {Orlando Poblete}",
year = "2014",
doi = "10.1590/1516-3180.2014.1321597",
language = "Portugu{\'e}s",
volume = "132",
pages = "15--22",
journal = "Sao Paulo Medical Journal",
issn = "1516-3180",
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number = "1",

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Acompanhamento de mulheres com células escamosas atípicas não pode excluir lesão intraepitelial de alto grau (ASC-H). / López-Alegría, Fanny; De Lorenzi, Dino Soares; Quezada, Orlando Poblete.

En: Sao Paulo Medical Journal, Vol. 132, N.º 1, 2014, p. 15-22.

Resultado de la investigación: Article

TY - JOUR

T1 - Acompanhamento de mulheres com células escamosas atípicas não pode excluir lesão intraepitelial de alto grau (ASC-H)

AU - López-Alegría, Fanny

AU - De Lorenzi, Dino Soares

AU - Quezada, Orlando Poblete

PY - 2014

Y1 - 2014

N2 - Context and Objective: The concept that the presence of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H) was introduced in the 2001 Bethesda System of cervical cytology classification. This nomenclature defines cervical cancer precursor lesions. The objective of this study was to investigate the colpocytological-histological results from a three-year follow-up conducted on a cohort of women with reports of ASC-H who were attended during 2005-2006 at clinics of the Southern Metropolitan Healthcare Service of Santiago, Chile. Design and Setting: Prospective cohort study at primary healthcare clinics in Santiago, Chile. Methods: Colpocytological-histological follow-up was conducted over a three-year period on 92 women with cytological reports of ASC-H who were attended at primary healthcare clinics during 2005-2006. Results: At the end of the follow-up period, high-grade lesions were evaluated and the following outcomes were observed: seven women presented invasive cancer (7.6%), 49 presented high-grade lesions (53.3%), 26 presented low-grade lesions (28.2%) and 10 presented normal results (10.9%). The "Conditional Probabilities Tree Diagram" was used to show the results from tests and the times of lesion detection. It demonstrated that, after a first report of ASC-H, clinical management needed to be interventionist. Conclusion: The follow-up on our cohort of women showed that the majority of uncertain ASC-H diagnoses (82.6%) had abnormal colposcopic results and that during the follow-up using ASC-H smears, two out of every three women developed high-grade lesions.

AB - Context and Objective: The concept that the presence of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions (ASC-H) was introduced in the 2001 Bethesda System of cervical cytology classification. This nomenclature defines cervical cancer precursor lesions. The objective of this study was to investigate the colpocytological-histological results from a three-year follow-up conducted on a cohort of women with reports of ASC-H who were attended during 2005-2006 at clinics of the Southern Metropolitan Healthcare Service of Santiago, Chile. Design and Setting: Prospective cohort study at primary healthcare clinics in Santiago, Chile. Methods: Colpocytological-histological follow-up was conducted over a three-year period on 92 women with cytological reports of ASC-H who were attended at primary healthcare clinics during 2005-2006. Results: At the end of the follow-up period, high-grade lesions were evaluated and the following outcomes were observed: seven women presented invasive cancer (7.6%), 49 presented high-grade lesions (53.3%), 26 presented low-grade lesions (28.2%) and 10 presented normal results (10.9%). The "Conditional Probabilities Tree Diagram" was used to show the results from tests and the times of lesion detection. It demonstrated that, after a first report of ASC-H, clinical management needed to be interventionist. Conclusion: The follow-up on our cohort of women showed that the majority of uncertain ASC-H diagnoses (82.6%) had abnormal colposcopic results and that during the follow-up using ASC-H smears, two out of every three women developed high-grade lesions.

KW - Biopsy

KW - Follow-up studies

KW - Neoplasms squamous cell

KW - Uterine cervical neoplasms

KW - Vaginal smears

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U2 - 10.1590/1516-3180.2014.1321597

DO - 10.1590/1516-3180.2014.1321597

M3 - Article

VL - 132

SP - 15

EP - 22

JO - Sao Paulo Medical Journal

JF - Sao Paulo Medical Journal

SN - 1516-3180

IS - 1

ER -