JAIME EDUARDO VILLEGAS OLAVARRIA

Bachelor in Biologicals Science, PhD in Sciences

    • 323 Citas
    • 11 Índice H
    19972019
    Los cambios que haya realizado en Pure se mostrarán aquí próximamente.

    Resultado de la investigación 1997 2019

    • 323 Citas
    • 11 Índice H
    • 18 Article
    • 2 Chapter
    • 1 Editorial
    2019

    HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes

    Villota, C., Varas-Godoy, M., Jeldes, E., Campos, A., Villegas, J., Borgna, V., Burzio, L. O. & Burzio, V. A., 1 ene 2019, En : Aging. 11, 1, p. 33-47 15 p.

    Resultado de la investigación: Article

    Antisense RNA
    Untranslated RNA
    Cell Aging
    Keratinocytes
    Down-Regulation

    Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors

    Fitzpatrick, C., Bendek, M. F., Briones, M., Farfán, N., Silva, V. A., Nardocci, G., Montecino, M., Boland, A., Deleuze, J. F., Villegas, J., Villota, C., Silva, V., Lobos-Gonzalez, L., Borgna, V., Barrey, E., Burzio, L. O. & Burzio, V. A., 1 jun 2019, En : Cell Death and Disease. 10, 6, 423.

    Resultado de la investigación: Article

    Acceso abierto
    Cell Cycle Checkpoints
    Cell Cycle
    Breast Neoplasms
    MicroRNAs
    Growth
    2017
    Papillomavirus Vaccines
    Chile
    Uterine Cervical Neoplasms
    Health
    Cause of Death

    Different cancers, same target?

    Villegas, J., Borgna, V. & Burzio, V. A., 1 ene 2017, En : Aging. 9, 8, p. 1853-1854 2 p.

    Resultado de la investigación: Editorial

    2 Citas (Scopus)

    In vivo knockdown of antisense non-coding mitochondrial RNAs by a lentiviral-encoded shRNA inhibits melanoma tumor growth and lung colonization

    Varas-Godoy, M., Lladser, A., Farfan, N., Villota, C., Villegas, J., Tapia, J. C., Burzio, L. O., Burzio, V. A. & Valenzuela, P. D. T., 1 ene 2017, (Accepted/In press) En : Pigment Cell and Melanoma Research. 31, 1, p. 64-72 9 p.

    Resultado de la investigación: Article

    Antisense RNA
    Untranslated RNA
    Small Interfering RNA
    Tumors
    Melanoma
    7 Citas (Scopus)

    Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model

    Borgna, V., Villegas, J., Burzio, V. A., Belmar, S., Araya, M., Jeldes, E., Lobos-González, L., Silva, V., Villota, C., Oliveira-Cruz, L., Lopez, C., Socias, T., Castillo, O. & Burzio, L. O., 2017, En : Oncotarget. 8, 27, p. 43692-43708 17 p.

    Resultado de la investigación: Article

    Renal Cell Carcinoma
    Antisense RNA
    Untranslated RNA
    Neoplasm Metastasis
    Growth

    Non-coding mitochondrial rnas (ncmtRNAs) in gynecological and urinary malignancies: Universal targets for development of an efficient therapy?

    Borgna, V., Lobos-González, L., Burzio, V., Araya, M., Ávila, R., Jeldes, E., Silva, V., Briones, M., Socias, T., Guevara, F., López, C., Villota, C., Bustamante, E., Bendex, M., Fitzpatrick, C., Burzio, L. O. & Villegas, J., 1 ene 2017, Horizons in Cancer Research. Nova Science Publishers, Inc., Vol. 65. p. 91-117 27 p.

    Resultado de la investigación: Chapter

    Untranslated RNA
    Long Noncoding RNA
    Antisense Oligonucleotides
    Neoplasms
    Therapeutics
    2016
    12 Citas (Scopus)

    Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors

    Lobos-González, L., Silva, V., Araya, M., Restovic, F., Echenique, J., Oliveira-Cruz, L., Fitzpatrick, C., Briones, M., Villegas, J., Villota, C., Vidaurre, S., Borgna, V., Socias, M., Valenzuela, S., Lopez, C., Socias, T., Varas, M., Díaz, J., Burzio, L. O. & Burzio, V. A., 1 ene 2016, En : Oncotarget. 7, 36, p. 58331-58350 20 p.

    Resultado de la investigación: Article

    Untranslated RNA
    Antisense RNA
    Melanoma
    Antisense Oligonucleotides
    Neoplasm Metastasis
    2014
    31 Citas (Scopus)

    Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy

    Vidaurre, S., Fitzpatrick, C., Burzio, V. A., Briones, M., Villota, C., Villegas, J., Echenique, J., Oliveira-Cruz, L., Araya, M., Borgna, V., Socías, T., Lopez, C., Avila, R. & Burzio, L. O., 26 sep 2014, En : Journal of Biological Chemistry. 289, 39, p. 27182-27198 17 p.

    Resultado de la investigación: Article

    Untranslated RNA
    Down-Regulation
    Cells
    Cell death
    Tumors
    1 Cita (Scopus)

    Long non coding mitochondrial RNAs as potential targets for diagnosis and therapy of bladder cancer

    Villegas, J., Rivas, A., Ávila, R., Borgna, V., Lobos-Gonzales, L., Burzio, V., López, C., Gomez, R., Landerer, E., Velarde, L. & Burzio, L. O., 1 ene 2014, Bladder Cancer. Nova Science Publishers, Inc., p. 95-116 22 p.

    Resultado de la investigación: Chapter

    Long Noncoding RNA
    Urinary Bladder Neoplasms
    Neoplasms
    Therapeutics
    Down-Regulation

    Long non-coding mitochondrial RNAs as potential targets for diagnosis and therapy of bladder cancer

    Villegas, J., Rivas, A., Ávila, R., Borgna, V., Lobos-Gonzales, L., Burzio, V., López, C., Gomez, R., Landerer, E., Velarde, L. & Burzio, L. O., 2014, En : International Journal of Cancer Research and Prevention. 7, 2, p. 147-162 16 p.

    Resultado de la investigación: Article

    Long Noncoding RNA
    Urinary Bladder Neoplasms
    Neoplasms
    Therapeutics
    Intravesical Administration
    2012
    22 Citas (Scopus)

    Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer

    Rivas, A., Burzio, V., Landerer, E., Borgna, V., Gatica, S., Ávila, R., López, C., Villota, C., De La Fuente, R., Echenique, J., Burzio, L. O. & Villegas, J., 2012, En : BMC Urology. 12, 37.

    Resultado de la investigación: Article

    Long Noncoding RNA
    Urinary Bladder Neoplasms
    Urine
    Tissue Donors
    Fluorescence In Situ Hybridization
    22 Citas (Scopus)

    Expression of mitochondrial non-coding RNAs (ncRNAs) is modulated by high risk human papillomavirus (HPV) oncogenes

    Villota, C., Campos, A., Vidaurre, S., Oliveira-Cruz, L., Boccardo, E., Burzio, V. A., Varas, M., Villegas, J., Villa, L. L., Valenzuela, P. D. T., Socías, M., Roberts, S. & Burzio, L. O., 15 jun 2012, En : Journal of Biological Chemistry. 287, 25, p. 21303-21315 13 p.

    Resultado de la investigación: Article

    Untranslated RNA
    Oncogenes
    Oncogenic viruses
    Cells
    Cell proliferation
    2011
    40 Citas (Scopus)

    Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells

    Landerer, E., Villegas, J., Burzio, V. A., Oliveira, L., Villota, C., Lopez, C., Restovic, F., Martinez, R., Castillo, O. & Burzio, L. O., ago 2011, En : Cellular Oncology. 34, 4, p. 297-305 9 p.

    Resultado de la investigación: Article

    Neoplasms
    In Situ Hybridization
    Heterochromatin
    Ribonucleases
    Confocal Microscopy
    2009
    60 Citas (Scopus)

    Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells

    Burzio, V. A., Villota, C., Villegas, J., Landerer, E., Boccardo, E., Villa, L. L., Martínez, R., Lopez, C., Gaete, F., Toro, V., Rodriguez, X. & Burzio, L. O., 9 jun 2009, En : Proceedings of the National Academy of Sciences of the United States of America. 106, 23, p. 9430-9434 5 p.

    Resultado de la investigación: Article

    Untranslated RNA
    Neoplasms
    Tumor Cell Line
    Nucleotides
    Cell Culture Techniques
    2007
    40 Citas (Scopus)

    Expression of a novel non-coding mitochondrial RNA in human proliferating cells

    Villegas, J., Burzio, V., Villota, C., Landerer, E., Martinez, R., Santander, M., Martinez, R., Pinto, R., Vera, M. I., Boccardo, E., Villa, L. L. & Burzio, L. O., 1 dic 2007, En : Nucleic Acids Research. 35, 21, p. 7336-7347 12 p.

    Resultado de la investigación: Article

    Untranslated RNA
    Nucleotides
    Aphidicolin
    Pancreatic Ribonuclease
    Phytohemagglutinins
    2003
    17 Citas (Scopus)

    The complete sequence of the mitochondrial genome of the Chinook salmon, Oncorhyncus tshawytscha

    Wilhelm, V., Villegas, J., Miquel, Á., Engel, E., Bernales, S., Valenzuela, P. D. T. & Burzio, L. O., 2003, En : Biological Research. 36, 2, p. 223-231 9 p.

    Resultado de la investigación: Article

    Mitochondrial Genome
    Trout
    Salmon
    Oncorhynchus tshawytscha
    Genes
    2002
    18 Citas (Scopus)

    A putative RNA editing from U to C in a mouse mitochondrial transcript

    Villegas, J., Müller, I., Arredondo, J., Pinto, R. & Burzio, L. O., 1 may 2002, En : Nucleic Acids Research. 30, 9, p. 1895-1901 7 p.

    Resultado de la investigación: Article

    RNA Editing
    RNA
    Genes
    DNA Restriction Enzymes
    Artifacts
    31 Citas (Scopus)

    Localization of the 16S mitochondrial rRNA in the nucleus of mammalian spermatogenic cells

    Villegas, J., Araya, P., Bustos-Obregon, E. & Burzio, L. O., 1 nov 2002, En : Molecular Human Reproduction. 8, 11, p. 977-983 7 p.

    Resultado de la investigación: Article

    Spermatocytes
    Spermatogenesis
    In Situ Hybridization
    Spermatozoa
    Sperm Head
    2000
    20 Citas (Scopus)

    A novel chimeric mitochondrial RNA localized in the nucleus of mouse sperm

    Villegas, J., Zarraga, A. M., Muller, I., Montecinos, L., Werner, E., Brito, M., Meneses, A. M. & Burzio, L. O., 2000, En : DNA and Cell Biology. 19, 9, p. 579-588 10 p.

    Resultado de la investigación: Article

    Spermatozoa
    RNA
    Testis
    Clone Cells
    Trans-Splicing
    1997

    A novel mitochondrial rna containing the 16s rRNA is present in mouse sperm cells

    Villegas, J., Zarraga, A. M., Montecinos, L., Brito, M., Werner, E. & Burzio, L. O., 1997, En : FASEB Journal. 11, 9

    Resultado de la investigación: Article

    Spermatozoa
    RNA
    Cell proliferation
    In Situ Hybridization
    Sperm Midpiece